Ribosomes unraveled: The path from variant to impact

2024-9-1

Overcoming drug-resistant tumors with selection gene drives

2024-9-1

Pooled endogenous protein tagging and recruitment for systematic profiling of protein function

2024-9-1

Identifying compound-protein interactions with knowledge graph embedding of perturbation transcriptomics

2024-9-1

Functional and dynamic profiling of transcript isoforms reveals essential roles of alternative splicing in interferon response

2024-9-1

Comparative modeling reveals the molecular determinants of aneuploidy fitness cost in a wild yeast model

2024-9-1

Human milk variation is shaped by maternal genetics and impacts the infant gut microbiome

2024-9-1

Missing regulatory effects and viral triggers explored for childhood-onset asthma

2024-9-1

CXCR4 orchestrates the TOX-programmed exhausted phenotype of CD8+ T cells via JAK2/STAT3 pathway

2024-9-1

Long genetic and social isolation in Neanderthals before their extinction

2024-9-1

An isoform-resolution transcriptomic atlas of colorectal cancer from long-read single-cell sequencing

2024-8-30

Predicting T cell receptor functionality against mutant epitopes

2024-8-15

Analysis across Taiwan Biobank, Biobank Japan, and UK Biobank identifies hundreds of novel loci for 36 quantitative traits

2024-8-15

Genetic and functional analysis of Raynaud’s syndrome implicates loci in vasculature and immunity

2024-8-13

ERCC2 mutations alter the genomic distribution pattern of somatic mutations and are independently prognostic in bladder cancer

2024-8-1

Isotype-aware inference of B cell clonal lineage trees from single-cell sequencing data

2024-8-1

Diversity of ribosomes at the level of rRNA variation associated with human health and disease

2024-8-1

Stable and robust Xi and Y transcriptomes drive cell-type-specific autosomal and Xa responses in vivo and in vitro in four human cell types

2024-8-1

Genomic patterns of somatic mutations provide new prognostic, therapeutic, and biological insights in cancer

2024-8-1

ONCOLINER: A new solution for monitoring, improving, and harmonizing somatic variant calling across genomic oncology centers

2024-8-1

Rhinovirus infection of airway epithelial cells uncovers the non-ciliated subset as a likely driver of genetic risk to childhood-onset asthma

2024-8-1

ABCA7-dependent induction of neuropeptide Y is required for synaptic resilience in Alzheimer’s disease through BDNF/NGFR signaling

2024-8-1

Quantification of escape from X chromosome inactivation with single-cell omics data reveals heterogeneity across cell types and tissues

2024-7-30

The centromere landscapes of four karyotypically diverse Papaver species provide insights into chromosome evolution and speciation

2024-7-30

Strategic targeting of Cas9 nickase induces large segmental duplications

2024-7-24

Rare variation in non-coding regions with evolutionary signatures contributes to autism spectrum disorder risk

2024-7-16

Comparative genomics illuminates karyotype and sex chromosome evolution of sharks

2024-7-11

Crosstalk between epitranscriptomic and epigenomic modifications and its implication in human diseases

2024-7-8

Implications of noncoding regulatory functions in the development of insulinomas

2024-7-2

Inverted triplications formed by iterative template switches generate structural variant diversity at genomic disorder loci

2024-7-1

Cell-type-specific loops linked to RNA polymerase II elongation in human neural differentiation

2024-7-1

Mudskipper detects combinatorial RNA binding protein interactions in multiplexed CLIP data

2024-7-1

Sepsis research: Heterogeneity as a foundation rather than an afterthought

2024-7-1

Exome-wide evidence of compound heterozygous effects across common phenotypes in the UK Biobank

2024-6-28

Evolutionary and biomedical implications of sex differences in the primate brain transcriptome

2024-6-27

Extreme overall mushroom genome expansion in Mycena s.s. irrespective of plant hosts or substrate specializations

2024-6-27

Rhesus macaque as a model for sex-biased neurological diseases

2024-6-27

Synthetic DNA barcodes identify singlets in scRNA-seq datasets and evaluate doublet algorithms

2024-6-25

Gene-environment interactions within a precision environmental health framework

2024-6-25

Neotelomeres and telomere-spanning chromosomal arm fusions in cancer genomes revealed by long-read sequencing

2024-6-24

eQTLs identify regulatory networks and drivers of variation in the individual response to sepsis

2024-6-18

SpRY-mediated screens facilitate functional dissection of non-coding sequences at single-base resolution

2024-6-17

Genome-wide association study of the common retinal disorder epiretinal membrane: Significant risk loci in each of three American populations

2024-6-1

Shaping human brain development and vulnerability through alternative splicing

2024-6-1

SIMS: A deep-learning label transfer tool for single-cell RNA sequencing analysis

2024-5-31

A gene with a thousand alleles: The hyper-variable effectors of plant-parasitic nematodes

2024-5-29

Regulatory barriers to US-China collaboration for generative AI development in genomic research

2024-5-24

Meningioma transcriptomic landscape demonstrates novel subtypes with regional associated biology and patient outcome

2024-5-23

Complete spatially resolved gene expression is not necessary for identifying spatial domains

2024-5-22

Lineage-specific splicing regulation of MAPT gene in the primate brain

2024-5-20