Repurposing an Endogenous CRISPR-Cas System to Generate and Study Subtle Mutations in Bacteriophages

2024-9-30

Characterization of Research Support of Genome Editing Technologies and Transition to Clinical Trials

2024-9-26

Genome Editing Therapy for the Blood: <i>Ex Vivo</i> Success and <i>In Vivo</i> Prospects

2024-9-26

Identification of a Guide RNA Targeting an Ultraconserved Element for Evaluation of Cas9 Genome Editors Across Mammalian Species

2024-9-23

Expanding the Genome-Editing Toolbox with <i>Abyssicoccus albus</i> Cas9 Using a Unique Protospacer Adjacent Motif Sequence

2024-8-1

AI and SynBio Meet CRISPR Heralding a New Genome Editing Era

2024-8-1

Prime Editing of Vascular Endothelial Growth Factor Receptor 2 Attenuates Angiogenesis <i>In Vitro</i>

2024-8-1

Challenging the Boundaries Between Treatment, Prevention, and Enhancement in Human Genome Editing

2024-7-8

A Story of Perseverance: An Interview with Matthew Porteus

2024-6-1

Surveying the State of CRISPR and Gene Editing

2024-6-1

Unveiling Off-Target Mutations in CRISPR Guide RNAs: Implications for Gene Region Specificity

2024-6-1

Establishment of a Cleavage-Based Single-Plasmid Dual-Luciferase Surrogate Reporter for the Cleavage Efficiency Evaluation of CRISPR-Cas12a Systems and Its Primary Application

2024-6-1

Novel off-Targeting Events Identified after Genome Wide Analysis of CRISPR-Cas Edited Pigs

2024-5-21

Viral Delivery of Compact CRISPR-Cas12f for Gene Editing Applications

2024-5-2

Making the Search for Genome Editing Tortured Phrases a Collective Effort

2024-4-1

Correction to: <i>A Fluorescent Reporter Mouse for In Vivo Assessment of Genome Editing with Diverse Cas Nucleases and Prime Editors</i> by Chen et al. <i>The CRISPR Journal,</i> 2023;6(6):570–582; DOI: 10.1089/crispr.2023.0048

2024-4-1

dCas9 Tells Tales: Probing Gene Function and Transcription Regulation in Cancer

2024-4-1

CRISPR Pigs Portend a New Era of Xenotransplantation

2024-4-1

Gene Editing in the Chagas Disease Vector <i>Rhodnius prolixus</i> by Cas9-Mediated ReMOT Control

2024-4-1

Correction to: <i>Generation of a Commercial-Scale Founder Population of Porcine Reproductive and Respiratory Syndrome Virus Resistant Pigs Using CRISPR-Cas</i> by Burger et al. <i>The CRISPR Journal,</i> 2023;7(1):12–28; DOI: 10.1089/crispr.2023.0061

2024-4-1

Increasing Knockin Efficiency in Mouse Zygotes by Transient Hypothermia

2024-4-1

Rapid Variant Pathogenicity Analysis by CRISPR Activation of <i>CRB1</i> Gene Expression in Patient-Derived Fibroblasts

2024-4-1

Diverse Class 2 CRISPR Effectors as Active Nucleases with Expanded Targeting Capabilities

2024-4-1

Generation of Human Isogenic Induced Pluripotent Stem Cell Lines with CRISPR Prime Editing

2024-2-1

Easy-to-Use CRISPR-Cas9 Genome Editing in the Cultured Pacific Abalone (<i>Haliotis discus hannai</i>)

2024-2-1

Acknowledgment of Reviewers 2023

2024-2-1

Generation of a Commercial-Scale Founder Population of Porcine Reproductive and Respiratory Syndrome Virus Resistant Pigs Using CRISPR-Cas

2024-2-1

Warrior Spirit: An Interview with Victoria Gray, Sickle Cell Pioneer

2024-2-1

“CRISPR” Mutations: Inaccurate Linguistic Variations and Misrepresentation of the CRISPR Acronym

2024-2-1

CRISPR Momentum in the Clinic and the Field

2024-2-1

<i>Correction to:</i> Programmable RNA Targeting Using CasRx in Flies, by Buchman, et al. <i>The CRISPR Journal 2020;3(3)164–176</i>; doi: 10.1089/crispr.2020.0018

2024-2-1

Whole-Genome Sequencing Reveals Rare Off-Target Mutations in <i>MC1R</i>-Edited Pigs Generated by Using CRISPR-Cas9 and Somatic Cell Nuclear Transfer

2024-2-1

Benchmark Software and Data for Evaluating CRISPR-Cas9 Experimental Pipelines Through the Assessment of a Calibration Screen

2024-1-2

<i>Special Issue</i>: CRISPR Trials

2023-12-1

Engineered Antiviral Sensor Targets Infected Mosquitoes

2023-12-1

First Drug Approval Rises the CRISPR Tide

2023-12-1

A Fluorescent Reporter Mouse for <i>In Vivo</i> Assessment of Genome Editing with Diverse Cas Nucleases and Prime Editors

2023-12-1

A PCR-Induced Mutagenesis-Restriction Fragment Length Polymorphism Method for the Detection of CRISPR-Induced Indels

2023-12-1

CRISPRi-Mediated Treatment of Dominant Rhodopsin-Associated Retinitis Pigmentosa

2023-12-1

Differential Divalent Metal Binding by SpyCas9's RuvC Active Site Contributes to Nonspecific DNA Cleavage

2023-12-1

Modified Cas9-Guided Oxford Nanopore Technology Sequencing Uncovers Single and Multiple Transgene Insertion Sites in a Zebrafish Melanoma Model

2023-12-1

The Expanding Dissemination and Distribution Patterns of Diverse CRISPR Plasmids by Addgene

2023-11-27

Correction to: <i>Genotyping MUltiplexed-Sequencing of CRISPR-Localized Editing (GMUSCLE): An Experimental and Computational Approach for Analyzing CRISPR-Edited Cells</i> by Zhang et al. <i>The CRISPR Journal</i>, 2023;6(5):462-472; DOI: 10.1089/crispr.2023.0021

2023-11-9

Correction to: <i>APOBEC Reporter Systems for Evaluating diNucleotide Editing Levels</i> by Rieffer et al. <i>The CRISPR Journal</i>, 2023;6(5):430–446; DOI: 10.1089/crispr.2023.0027

2023-11-9

Germline Editing of <i>Drosophila</i> Using CRISPR-Cas9-Based Cytosine and Adenine Base Editors

2023-11-2

<i>Special Issue</i>: CRISPR Trials

2023-10-1

Genotyping MUltiplexed-Sequencing of CRISPR-Localized Editing (GMUSCLE): An Experimental and Computational Approach for Analyzing CRISPR-Edited Cells

2023-10-1

The CRISPR Toolbox: The End of the Beginning

2023-10-1

Advances in Cas12a-Based Amplification-Free Nucleic Acid Detection

2023-9-26

Enhancing Precision and Efficiency of Cas9-Mediated Knockin Through Combinatorial Fusions of DNA Repair Proteins

2023-9-15