Network modeling links kidney developmental programs and the cancer type-specificity of VHL mutations

2024-10-3

A web portal for exploring kinase-substrate interactions

2024-10-3

Calibrating tumor growth and invasion parameters with spectral spatial analysis of cancer biopsy tissues

2024-10-2

Inertial effect of cell state velocity on the quiescence-proliferation fate decision

2024-10-2

Neutral evolution of rare cancer mutations in the computer and the clinic

2024-10-2

Systems biology approach for enhancing limonene yield by re-engineering Escherichia coli

2024-10-1

Spatial interactions modulate tumor growth and immune infiltration

2024-9-30

Time and dose selective glucose metabolism for glucose homeostasis and energy conversion in the liver

2024-9-30

Identifying biomarkers for treatment of uveal melanoma by T cell engager using a QSP model

2024-9-30

Mathematical modeling insights into improving CAR T cell therapy for solid tumors with bystander effects

2024-9-28

Understanding flux switching in metabolic networks through an analysis of synthetic lethals

2024-9-17

Optimal performance objectives in the highly conserved bone morphogenetic protein signaling pathway

2024-9-14

Tipping-point transition from transient to persistent inflammation in pancreatic islets

2024-9-12

EpiScan: accurate high-throughput mapping of antibody-specific epitopes using sequence information

2024-9-9

Codon usage and expression-based features significantly improve prediction of CRISPR efficiency

2024-9-3

A Boolean model explains phenotypic plasticity changes underlying hepatic cancer stem cells emergence

2024-9-2

Network topology and interaction logic determine states it supports

2024-8-28

Recovering biomolecular network dynamics from single-cell omics data requires three time points

2024-8-27

Constraint-based modelling predicts metabolic signatures of low and high-grade serous ovarian cancer

2024-8-24

SignalingProfiler 2.0 a network-based approach to bridge multi-omics data to phenotypic hallmarks

2024-8-23

Assessing structural uncertainty of biochemical regulatory networks in metabolic pathways under varying data quality

2024-8-22

Integrated-omics analysis with explainable deep networks on pathobiology of infant bronchiolitis

2024-8-22

Using DeepSignalingFlow to mine signaling flows interpreting mechanism of synergy of cocktails

2024-8-21

Spatial computational modelling illuminates the role of the tumour microenvironment for treating glioblastoma with immunotherapies

2024-8-18

Insights gained from computational modeling of YAP/TAZ signaling for cellular mechanotransduction

2024-8-15

Practical parameter identifiability and handling of censored data with Bayesian inference in mathematical tumour models

2024-8-14

Hybridizing mechanistic modeling and deep learning for personalized survival prediction after immune checkpoint inhibitor immunotherapy

2024-8-14

A practically efficient algorithm for identifying critical control proteins in directed probabilistic biological networks

2024-8-12

Transient frequency preference responses in cell signaling systems

2024-8-11

High-affinity biomolecular interactions are modulated by low-affinity binders

2024-8-10

Author Correction: Network-driven cancer cell avatars for combination discovery and biomarker identification for DNA damage response inhibitors

2024-8-8

Modelling HIV-1 control and remission

2024-8-8

On the salient limitations of the methods of assembly theory and their classification of molecular biosignatures

2024-8-7

Phenotype prediction using biologically interpretable neural networks on multi-cohort multi-omics data

2024-8-2

Bifurcations in coupled amyloid-β aggregation-inflammation systems

2024-7-30

A possible path to persistent re-entry waves at the outlet of the left pulmonary vein

2024-7-23

Self-consistent signal transduction analysis for modeling context-specific signaling cascades and perturbations

2024-7-19

Including glutamine in a resource allocation model of energy metabolism in cancer and yeast cells

2024-7-18

A deep position-encoding model for predicting olfactory perception from molecular structures and electrostatics

2024-7-17

Systems modeling of oncogenic G-protein and GPCR signaling reveals unexpected differences in downstream pathway activation

2024-7-16

Cancer mutationscape: revealing the link between modular restructuring and intervention efficacy among mutations

2024-7-13

Benchmarking and integrating human B-cell receptor genomic and antibody proteomic profiling

2024-7-12

Computational gastronomy: capturing culinary creativity by making food computable

2024-7-8

A comprehensive review of computational cell cycle models in guiding cancer treatment strategies

2024-7-5

Revisiting the evolution of bow-tie architecture in signaling networks

2024-6-29

Longitudinal single-cell data informs deterministic modelling of inflammatory bowel disease

2024-6-24

Network-driven cancer cell avatars for combination discovery and biomarker identification for DNA damage response inhibitors

2024-6-21

Canalization reduces the nonlinearity of regulation in biological networks

2024-6-13

interFLOW: maximum flow framework for the identification of factors mediating the signaling convergence of multiple receptors

2024-6-10

Low-frequency ERK and Akt activity dynamics are predictive of stochastic cell division events

2024-6-4