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ACS Medicinal Chemistry Letters

短名	ACS Med. Chem. Lett.
Journal Impact	3.38
国际分区	CHEMISTRY, MEDICINAL(Q2)
期刊索引	SCI Q2中科院 3 区

ISSN	1948-5875
h-index	86
国内分区	医学(3区)医学药物化学(3区)

ACS 药物化学快报欢迎提交关于药物化学各个方面的手稿。该杂志将发表涉及广泛主题的研究，包括化合物的设计与优化、生物评估、药物递送、显像剂以及大分子和小分子药物的药理学。具体领域包括但不限于：先导生物活性分子和药物（小分子和生物制剂）的鉴定、合成和优化；在药物发现背景下新分子实体的生物学表征；用于鉴定或确认的计算、化学信息学和结构研究；生物活性分子、配体及其靶标的SAR分析；新的和改进的方法，包括辐射生物化学，广泛应用于药物化学；合成和天然（植物及其他）来源的生物活性分子的发现技术；解决机制的药代动力学/药效学研究；潜在的药物处置和反应，用于增强药物设计；以及药物化学转化为临床的药物遗传学和药物基因组学研究，机械药物代谢和代谢酶基因表达的调节与药物化学相关的化学专利。

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涉及主题	生物化学生物化学医学遗传学内科学有机化学药理学物理立体化学计算机科学基因核磁共振体外生物信息学受体组合化学酶计算生物学细胞生物学
出版信息	出版商: American Chemical Society，出版周期: ，期刊类型: journal
基本数据	创刊年份: 2010，原创研究文献占比: 100.00%，自引率:5.70%， Gold OA占比: 16.64%
平均审稿周期	网友分享经验：一般,3-8周

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Evaluation of High-Affinity Monoclonal Antibodies and Antibody-Drug Conjugates by Homogenous Time-Resolved FRET

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Inhibitors of Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MK2) as Treatment for Inflammatory Diseases

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ACS Medicinal Chemistry Letters

阅读文献时，研飞即可帮你快速了解期刊，查询影响因子与分区，智能高亮期刊预警！

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最新文章

Call for Papers: Academic and Industrial Collaborations in Drug Discovery

Cyclic Glycopeptide Analogs of Endomorphin-1 Provide Highly Effective Antinociception in Male and Female Mice

Design, Biological Characterization, and Discovery of Novel Cyclohexenyl Derivatives as Kinesin KIF18A Inhibitors for the Treatment of Ovarian Cancer

BODIPYS Based Fluorescent Markers To Monitor Autophagic Lysosomes and Lipid Droplets in TNBC

Issue Editorial Masthead

Rapid Affinity and Microsomal Stability Ranking of Crude Mixture Libraries of Histone Deacetylase Inhibitors

Structure–Activity Relationship of Potent, Selective, and Orally Bioavailable Molecular Glue Degraders of CK1α

Issue Publication Information

In This Issue, Volume 15, Issue 8

Discovery of BAY 2666605, a Molecular Glue for PDE3A and SLFN12

Correlating Predicted Reactivities with Experimental Inhibition Data of Covalent ChlaDUB1 Inhibitors

Nanogel–Carbon Dot Conjugates: A Synergistic Approach for Enhanced Cancer Treatment through Combination Therapy

Facile Synthesis of FimH Antagonist and Its Analogues: Simple Entry to Complex <i>C</i>-Mannoside Inhibitors of <i>E. coli</i> Adhesion

Discovery of Novel Nonpeptidic Proteasome Inhibitors Using Covalent Virtual Screening and Biological Evaluation

Identification of Potent CDK9 Inhibitors with Novel Skeletons via Virtual Screening, Biological Evaluation, and Molecular Dynamics Simulation

Neuroprotective Effect of 2-(Benzyloxy)arylureas Is Not Related to CypD Inhibition nor Suppression of mPTP Opening

Design, Synthesis, and Structural Evaluation of Acetylated Phenylthioketone Inhibitors of HDAC10

Synthesis and In Vivo Profiling of Desymmetrized Antimalarial Trioxolanes with Diverse Carbamate Side Chains

Side Chain Investigation of Imidazopyridazine as a Hinge Binder for Targeting Actionable Mutations of RET Kinase

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Evaluation of High-Affinity Monoclonal Antibodies and Antibody-Drug Conjugates by Homogenous Time-Resolved FRET

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Inhibitors of Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MK2) as Treatment for Inflammatory Diseases

Asymmetric Dirhodium-Catalyzed Modification of Immunomodulatory Imide Drugs and Their Biological Assessment

SAR Study of 4,8-Disubstituted Pyrimido[5,4-<i>d</i>]pyrimidines Exhibiting Antitrypanosomal and Antileishmanial Activity

Inhibitors of the Cyclic GMP-AMP Synthase (cGAS) as Potential Treatment for Autoimmune and Inflammatory Diseases

Design and Synthesis of c-Met and HDAC Dual Inhibitors for the Treatment of Breast Cancer

Structure–Activity Relationship of Truncated 4′-Selenonucleosides: A<sub>3</sub> Adenosine Receptor Activity and Binding Selectivity

Novel Heteroaryl Fluoroalkenes as DGK Inhibitors for Treating Cancer, Particularly Metastatic Melanoma

New Directions in Antibacterial, Anticancer, and Gene Editing Therapies

Innovative Drug Discovery: Targeting Cancer, Neurological Disorders, and Obesity

9,10-Bis[(4-(2-hydroxyethyl)piperazine-1-yl)prop2-yne-1-yl]anthracene: G-Quadruplex Selectivity and Anticancer Activity

Highly Selective Novel Heme Oxygenase-1 Hits Found by DNA-Encoded Library Machine Learning beyond the DEL Chemical Space

Advancements in Targeted Therapeutics: Integrating Metabolic Modulation, Immune Engineering, and Biologic Formulation Technologies

Emerging Techniques in Cancer Therapy: Precision Targeting for Improved Outcomes

Current Trends in Psychedelic Science: Integrating Modified Lysergic Acid Derivatives and Psilocybin in Modern Medicine

Novel Triazolopyridine Derivatives as DGAT2 Inhibitors for Treating Multiple Diseases

Exploring the Therapeutic Potential of Entheogens in Postoperative Cognitive Decline and Psychological Resilience

MALT1 Inhibitors for Treating Cancer and Immunological Diseases

Analysis of Antiangiogenic Potential and Cell Death Mechanism of a Kinetically Inert Platinum Antitumor Agent

Study of Chalcogen Aspirin Derivatives with Carbonic Anhydrase Inhibitory Properties for Treating Inflammatory Pain

Announcing the Early Career Board of <i>ACS Medicinal Chemistry Letters</i>

Benign-by-Design SAHA Analogues for Human and Animal Vector-Borne Parasitic Diseases

Discovery and Optimization of Aryl Piperidinone Ureas as Selective Formyl Peptide Receptor 2 Agonists

High-Throughput Assessment of Bile Salt Export Pump Inhibition Using RapidFire-MS and DESI-MS

Issue Publication Information

Issue Editorial Masthead

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帮你贴心管理全部的文献
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