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Medicinal Chemistry

短名	MC
Journal Impact	1.83
国际分区	CHEMISTRY, MEDICINAL(Q3)
期刊索引	SCI Q3中科院 4 区

ISSN	1573-4064, 1875-6638
h-index	50
国内分区	医学(4区)医学药物化学(4区)

《Medicinal Chemistry》是一本经过同行评审的期刊，旨在涵盖药物化学和合理药物设计领域的最新杰出进展。该期刊发表原创研究、小型评论文章以及客座编辑的主题专刊，涉及该领域的最新研究和发展。通过充分利用互联网技术进行稿件提交和同行评审，文章得以快速发表。药物化学是所有参与药物设计和发现的研究人员的重要期刊。

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涉及主题	生物化学生物化学医学遗传学有机化学内科学立体化学物理药理学体外核磁共振组合化学基因计算机科学酶内分泌学心理学生物信息学免疫学
出版信息	出版商: Bentham Science Publishers，出版周期: Bimonthly，期刊类型: journal
基本数据	创刊年份: 2005，原创研究文献占比: 80.49%，自引率:5.30%， Gold OA占比: 0.41%
平均审稿周期	网友分享经验：平均12.0个月
平均录用比例	网友分享经验：容易

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Benzimidazole Conjugates as Multi-target Anticancer Agents - A Comprehensive Review

2024-9-27

Design and Synthesis of (2,3-dichloro-4-(3-(substituted Phenyl)acryloyl) phenoxy) Substituted Carboxylic Acid as Potent Glutathione-s-transferase Inhibitors, Anti-breast-cancer Agents and Enhancing Therapeutic Efficacy of Anticancer Agents

2024-9-26

One-Pot Synthesis of Benzoxazoles: A Promising Approach to Aromatic Heterocyclic Compounds Preparation

2024-9-25

Examination of Triazolinedione-Derived Dihydropyrrole Hybrid Compounds: ER Stress-Related Apoptosis in Breast Cancer Cells, Molecular Docking, and ADMET Analysis

2024-9-25

In Silico Analysis and Molecular Docking of Human Antimicrobial Peptides for Targeting Monkeypox Virus: Potential Therapeutic Implications of Histatin 5 Peptide

2024-9-20

Pharmacological Evaluation of Bioisosterically Replaced and TriazoleTethered Derivatives for Anticancer Therapy

2024-9-19

Design, Synthesis, Anti-Proliferative Effects, and Mechanistic Details of Fluorine-Containing Biguanide Derivatives with Various Carbon Rings

2024-9-18

Synthesis, Characterization, and In vitro and In Silico Studies of New Triazole Derivatives as Aromatase Inhibitors

2024-9-18

Exploring Quinoline Derivatives: Their Antimalarial Efficacy and Structural Features

2024-9-11

Exploring Cannabis sativa L for Anti-Alzheimer Potential: An Extensive Computational Study including Molecular Docking, Molecular Dynamics, and ADMET Assessments

2024-9-11

Design and Synthesis of 3-(Phenylsulfonamido)benzamide Derivatives as Potent Carbonic Anhydrase IX Inhibitors: Biological Evaluations and Molecular Modeling Studies

2024-9-10

In Silico Studies of Phytoconstituents to Identify Potential Inhibitors for ERα Protein of Breast Cancer

2024-9-5

A Preclinical Study on 4-Methyl-N-((4-(trifluoromethoxy)phenyl) carbamoyl)-benzenesulfonamide as a Potent Chemotherapeutic Agent against Liver and Pancreatic Carcinogenesis in Rats: Immunohistochemical and Histopathological Studies

2024-9-4

Exploring the Diverse Therapeutic Applications of 1, 3-Thiazine: A Comprehensive Review

2024-8-30

Mapping the Landscape of Global Anticancer Organometallics Research: A Systematic Review

2024-8-29

Unveiling the Anti-cancer Potential of Oxadiazole Derivatives: A Comprehensive Exploration of Structure-Activity Relationships and Chemico-Biological Insights

2024-8-29

Recent Advances in Anticancer Research of Osmium and Rhodium Complexes

2024-8-29

Docking and Molecular Dynamics Studies on Anticancer Activities of Flavonoids as Inhibitors of CDK2 and CDK9

2024-8-28

New Approach as Inhibitor Against Head-Neck Cancer by In silico, DFT, FMOs, Docking, Molecular Dynamic, and ADMET of Euphorbia tirucalli (Pencil Cactus)

2024-8-27

Platinum Group Metals against Parasites: State of the Art and Future Perspectives

2024-8-23

Acknowledgements to Reviewers

2024-8-15

Synthesis and Evaluation of Antibacterial and Antifungal Activities In vitro and In silico of Novel Morpholinoalkoxychalcones

2024-8-8

Exploring Thiophene Derivatives: Synthesis Strategies and Biological Significance

2024-8-8

In vitro and In vivo Activity of a New N-Oxide Derivative for Acne Vulgaris Treatment

2024-7-30

A Computational Approach Using α-Carbonic Anhydrase to Find Anti-Trypanosoma cruzi Agents

2024-7-30

Chemically Synthesized 1,2,3,4,6-Pentakis-O-Galloyl-β-D-Glucopyranoside Blocks SARS-CoV-2 Spike Interaction with Host ACE-2 Receptor

2024-7-22

N,N-Disubstituted 4-sulfamoylbenzoic Cid Derivatives as Inhibitors of Cytosolic Phospholipase A2α: Synthesis, Aqueous Solubility, and Activity in a Vesicle and a Whole Blood Assay

2024-7-22

Crucial Structural Understanding for Selective HDAC8 Inhibition: Common Pharmacophores, Molecular Docking, Molecular Dynamics, and Zinc Binder Analysis of selective HDAC8 inhibitors

2024-7-19

Synthesis and Biological Evaluation of Amino Acid and Peptide Conjugates of 5-Bromovaleric Acid

2024-7-8

The Catalysts-Based Synthetic Approaches to Quinolines: A Review

2024-6-24

Design, Synthesis, and Evaluation of Antifungal Activity of Pyrazoleacetamide Derivatives

2024-6-13

An Overview of the Pharmacological Activities and Synthesis of Benzothiophene Derivatives

2024-6-10

In silico and In vitro Assessment of Dimeric Flavonoids (Brachydins) on Rhipicephalus microplus Glutathione S-transferase

2024-6-5

Targeting Diabetes with Azole-derived Medicinal Agents

2024-6-4

New 3-Hydroxypyridine-4-one Analogues: Their Synthesis, Antimicrobial Evaluation, Molecular Docking, and In Silico ADME Prediction

2024-6-4

Efficient Synthesis of Mannopyranoside-based Fatty Acyl Esters: Effects of Acyl Groups on Antimicrobial Potential

2024-6-4

In Silico Discovery and Predictive Modeling of Novel Acetylcholinesterase (AChE) Inhibitors for Alzheimer's Treatment

2024-5-28

New Thieno[2,3-d]pyrimidines as Anticancer VEGFR-2 Inhibitors with Apoptosis Induction: Design, Synthesis, and Biological and In Silico Studies

2024-5-24

Pyrazole Paradigms: Unveiling Synthetic Pathways and Unraveling Anti-Cancer Potential

2024-5-17

In vitro and In vivo Biological Activity of Two Aryloxy-naphthoquinones in Mice Infected with Trypanosoma cruzi Strains

2024-5-16

Natural Products Inspired Drug Discovery for Infectious Diseases

2024-5-14

PPARs (Peroxisome Proliferator-activated Receptors) and Their Agonists in Alzheimer's Disease

2024-5-9

Synthesis and Antibacterial Evaluation of Novel Small-Molecule Antibacterials of a Reduced Acridine Structure in S. aureus Strains Including MRSA

2024-5-9

Synthetic Protocols, Structural Activity Relationship, and Biological Activity of Piperazine and its Derivatives

2024-4-29

Synthesis, Molecular Docking Studies and Biological Evaluation of Thiazolyl Hydrazone Derivatives of Chromone-3-carbaldehyde as Potent Anti-Oxidant and Anti-Inflammatory Agents

2024-4-26

Substituted 4H-3,1-benzoxazine-4-one Derivatives as Inhibitors of Cathepsin G

2024-4-26

Unveiling Therapeutic Avenues for Crohn’s Disease Management: Exploring Inhibitors for Adherent-Invasive Escherichia coli Propanediol Dehydratase

2024-4-24

Computational Chemistry: Prediction of Compound Accessibility of Targeted Synthesized Compounds

2024-4-17

Antimicrobial Potential of Polyphenols: An Update on Alternative for Combating Antimicrobial Resistance

2024-4-15

A Computational Study of Green Tea Extracts and their Derivatives as Potential Inhibitors for Squalene Monooxygenase

2024-4-5

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Medicinal Chemistry

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最新文章

Benzimidazole Conjugates as Multi-target Anticancer Agents - A Comprehensive Review

Design and Synthesis of (2,3-dichloro-4-(3-(substituted Phenyl)acryloyl) phenoxy) Substituted Carboxylic Acid as Potent Glutathione-s-transferase Inhibitors, Anti-breast-cancer Agents and Enhancing Therapeutic Efficacy of Anticancer Agents

One-Pot Synthesis of Benzoxazoles: A Promising Approach to Aromatic Heterocyclic Compounds Preparation

Examination of Triazolinedione-Derived Dihydropyrrole Hybrid Compounds: ER Stress-Related Apoptosis in Breast Cancer Cells, Molecular Docking, and ADMET Analysis

In Silico Analysis and Molecular Docking of Human Antimicrobial Peptides for Targeting Monkeypox Virus: Potential Therapeutic Implications of Histatin 5 Peptide

Pharmacological Evaluation of Bioisosterically Replaced and TriazoleTethered Derivatives for Anticancer Therapy

Design, Synthesis, Anti-Proliferative Effects, and Mechanistic Details of Fluorine-Containing Biguanide Derivatives with Various Carbon Rings

Synthesis, Characterization, and In vitro and In Silico Studies of New Triazole Derivatives as Aromatase Inhibitors

Exploring Quinoline Derivatives: Their Antimalarial Efficacy and Structural Features

Exploring Cannabis sativa L for Anti-Alzheimer Potential: An Extensive Computational Study including Molecular Docking, Molecular Dynamics, and ADMET Assessments

Design and Synthesis of 3-(Phenylsulfonamido)benzamide Derivatives as Potent Carbonic Anhydrase IX Inhibitors: Biological Evaluations and Molecular Modeling Studies

In Silico Studies of Phytoconstituents to Identify Potential Inhibitors for ERα Protein of Breast Cancer

A Preclinical Study on 4-Methyl-N-((4-(trifluoromethoxy)phenyl) carbamoyl)-benzenesulfonamide as a Potent Chemotherapeutic Agent against Liver and Pancreatic Carcinogenesis in Rats: Immunohistochemical and Histopathological Studies

Exploring the Diverse Therapeutic Applications of 1, 3-Thiazine: A Comprehensive Review

Mapping the Landscape of Global Anticancer Organometallics Research: A Systematic Review

Unveiling the Anti-cancer Potential of Oxadiazole Derivatives: A Comprehensive Exploration of Structure-Activity Relationships and Chemico-Biological Insights

Recent Advances in Anticancer Research of Osmium and Rhodium Complexes

Docking and Molecular Dynamics Studies on Anticancer Activities of Flavonoids as Inhibitors of CDK2 and CDK9

New Approach as Inhibitor Against Head-Neck Cancer by In silico, DFT, FMOs, Docking, Molecular Dynamic, and ADMET of Euphorbia tirucalli (Pencil Cactus)

Platinum Group Metals against Parasites: State of the Art and Future Perspectives

Acknowledgements to Reviewers

Synthesis and Evaluation of Antibacterial and Antifungal Activities In vitro and In silico of Novel Morpholinoalkoxychalcones

Exploring Thiophene Derivatives: Synthesis Strategies and Biological Significance

In vitro and In vivo Activity of a New N-Oxide Derivative for Acne Vulgaris Treatment

A Computational Approach Using α-Carbonic Anhydrase to Find Anti-Trypanosoma cruzi Agents

Chemically Synthesized 1,2,3,4,6-Pentakis-O-Galloyl-β-D-Glucopyranoside Blocks SARS-CoV-2 Spike Interaction with Host ACE-2 Receptor

N,N-Disubstituted 4-sulfamoylbenzoic Cid Derivatives as Inhibitors of Cytosolic Phospholipase A2α: Synthesis, Aqueous Solubility, and Activity in a Vesicle and a Whole Blood Assay

Crucial Structural Understanding for Selective HDAC8 Inhibition: Common Pharmacophores, Molecular Docking, Molecular Dynamics, and Zinc Binder Analysis of selective HDAC8 inhibitors

Synthesis and Biological Evaluation of Amino Acid and Peptide Conjugates of 5-Bromovaleric Acid

The Catalysts-Based Synthetic Approaches to Quinolines: A Review

Design, Synthesis, and Evaluation of Antifungal Activity of Pyrazoleacetamide Derivatives

An Overview of the Pharmacological Activities and Synthesis of Benzothiophene Derivatives

In silico and In vitro Assessment of Dimeric Flavonoids (Brachydins) on Rhipicephalus microplus Glutathione S-transferase

Targeting Diabetes with Azole-derived Medicinal Agents

New 3-Hydroxypyridine-4-one Analogues: Their Synthesis, Antimicrobial Evaluation, Molecular Docking, and In Silico ADME Prediction

Efficient Synthesis of Mannopyranoside-based Fatty Acyl Esters: Effects of Acyl Groups on Antimicrobial Potential

In Silico Discovery and Predictive Modeling of Novel Acetylcholinesterase (AChE) Inhibitors for Alzheimer's Treatment

New Thieno[2,3-d]pyrimidines as Anticancer VEGFR-2 Inhibitors with Apoptosis Induction: Design, Synthesis, and Biological and In Silico Studies

Pyrazole Paradigms: Unveiling Synthetic Pathways and Unraveling Anti-Cancer Potential

In vitro and In vivo Biological Activity of Two Aryloxy-naphthoquinones in Mice Infected with Trypanosoma cruzi Strains

Natural Products Inspired Drug Discovery for Infectious Diseases

PPARs (Peroxisome Proliferator-activated Receptors) and Their Agonists in Alzheimer's Disease

Synthesis and Antibacterial Evaluation of Novel Small-Molecule Antibacterials of a Reduced Acridine Structure in S. aureus Strains Including MRSA

Synthetic Protocols, Structural Activity Relationship, and Biological Activity of Piperazine and its Derivatives

Synthesis, Molecular Docking Studies and Biological Evaluation of Thiazolyl Hydrazone Derivatives of Chromone-3-carbaldehyde as Potent Anti-Oxidant and Anti-Inflammatory Agents

Substituted 4H-3,1-benzoxazine-4-one Derivatives as Inhibitors of Cathepsin G

Unveiling Therapeutic Avenues for Crohn’s Disease Management: Exploring Inhibitors for Adherent-Invasive Escherichia coli Propanediol Dehydratase

Computational Chemistry: Prediction of Compound Accessibility of Targeted Synthesized Compounds

Antimicrobial Potential of Polyphenols: An Update on Alternative for Combating Antimicrobial Resistance

A Computational Study of Green Tea Extracts and their Derivatives as Potential Inhibitors for Squalene Monooxygenase

帮你贴心管理全部的文献研飞ivySCI，高效的论文管理

帮你贴心管理全部的文献
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