磁共振概念 A 部分汇集了参与磁共振技术应用的临床医生、化学家和物理学家。该杂志欢迎主要来自磁共振成像 (MRI)、核磁共振 (NMR) 和电子顺磁共振 (EPR) 领域的投稿，但也鼓励与不太常见的磁共振成像和分析方法相关的投稿。投稿人来自学术界，政府和临床社区，传播医学、非医学和分析磁共振方法的最新重要实验结果，以及相关的计算和理论进展。主题领域包括（但不限于）：-磁共振理解的基本进展-磁共振成像的实验结果（包括 MRI 及其专业应用）-磁共振波谱的实验结果（包括 NMR、EPR 及其专业应用）-实验的计算和理论支持与预测以结果为中心的评论提供评论和 D讨论专题研究领域的最新成果和发展-使用教程或教育方法回顾磁共振方法

Concepts in Magnetic Resonance Part A: Bridging Education and Research brings together clinicians, chemists, and physicists involved in the application of magnetic resonance technology. This journal welcomes submissions primarily from the fields of Magnetic Resonance Imaging (MRI), Nuclear Magnetic Resonance (NMR), and Electron Paramagnetic Resonance (EPR), while also encouraging contributions related to less common magnetic resonance imaging and analytical methods. Contributors come from academia, government, and the clinical community, disseminating the latest significant experimental results in medical, non-medical, and analytical magnetic resonance methods, as well as related computational and theoretical advancements. The subject areas include (but are not limited to): - Fundamental advancements in understanding magnetic resonance - Experimental results in magnetic resonance imaging (including MRI and its specialized applications) - Experimental results in magnetic resonance spectroscopy (including NMR, EPR, and their specialized applications) - Computational and theoretical support and predictions for experiments - Results-oriented reviews and discussions - Latest findings and developments in specialized research areas - Reviews of magnetic resonance methods using tutorials or educational approaches.

《Concepts in Magnetic Resonance Part A: Bridging Education and Research》汇集了参与磁共振技术应用的临床医生、化学家和物理学家。该杂志欢迎来自磁共振成像 (MRI)、核磁共振 (NMR) 和电子顺磁共振 (EPR) 领域的投稿，同时也鼓励与不太常见的磁共振成像和分析方法相关的研究。投稿人包括学术界、政府和临床社区的研究者，旨在传播医学、非医学和分析磁共振方法的最新重要实验结果，以及相关的计算和理论进展。主题领域包括（但不限于）：- 磁共振理解的基本进展 - 磁共振成像的实验结果（包括 MRI 及其专业应用） - 磁共振波谱的实验结果（包括 NMR、EPR 及其专业应用） - 实验的计算和理论支持与预测 - 以结果为中心的评论和讨论 - 专题研究领域的最新成果和发展 - 使用教程或教育方法回顾磁共振方法

Concepts in Magnetic Resonance Part A: Bridging Education and Research

The density matrix of an arbitrary pure state of a system consisting of two spin‐1/2 particles is derived from the Pauli spin angular momentum operators. Mixed singlet and triplet states are then formed from linear combinations of pure states and their corresponding density matrices constructed. Singlet and triplet states are exemplified by the spin isomers parahydrogen and orthohydrogen, respectively. Partial mixing is illustrated with the example of bilinear spin–spin coupling. Various properties of the density matrices of pure and mixed states are discussed, including idempotence, factoring, and spin correlation.

Eric R. Johnston

Concepts in Magnetic Resonance Part A

Density Matrix of Two Spin‐1/2 Particles: Pure and Mixed States

两个自旋-1/2粒子的密度矩阵：纯态与混合态

Abstract The sensitivity of NMR relaxation to molecular motion is explored to study the aging of polymer materials and paint binder in master paintings. Polymeric materials are formulated from macromolecules with a distribution of molecular weights and low molecular weight additives. Their physical and chemical properties change with time due to exposure to temperature, mechanical stress, and solvents. These conditions lead to physical and chemical aging, which can proceed naturally over longer times or accelerated under artificial conditions in shorter times. Either procedure bears a particular signature on the molecular mobility, which can be probed nondestructively by the NMR relaxation times T 1 and T 2 . Natural aging and accelerated temperature‐ and solvent‐induced aging are summarized for synthetic polymer materials and compared to aging of binders in the paint layers of paintings aged naturally over hundreds of years and aged artificially by solvent‐cleaning procedures during restoration or at elevated temperature during forgery.

Bernhard Blümich

Aging of polymeric materials by stray‐field NMR relaxometry with the NMR ‐ MOUSE

聚合物材料的老化研究：利用NMR-MOUSE进行杂散场NMR弛豫测量

Abstract We present a tutorial discussion of diffusion measurements by NMR, aimed around a specific problem. To measure diffusion in the presence of convective flow, one may use the second echo using the well‐known cancellation of phase effects from flow for the second echo. In testing this with a simple organic liquid and a static (dc) gradient at room temperature, where no convection can occur, we noticed the data from the second echo implied a substantially larger rate of diffusion than for the first echo. The error is due to the second echo being a superposition of a spin (Hahn) echo (an echo of the first echo) and a stimulated echo. We show that the stimulated echo is more attenuated by diffusion (it has a larger b value), explaining our result. A simple phase cycle is presented that suppresses the stimulated echo and leads to the correct diffusion value from the second echo. That is, the diffusion values taken from the first and second echoes are now identical.

Hilary T. Fabich

Partha Nandi

Hans Thomann

Mark S. Conradi

Diffusion measurements using the second echo

使用第二回波的扩散测量

Abstract This mini‐review considers the scientific and historical development of the constant 1.26 T 2 , which represents the acquisition time for which the signal‐to‐noise ratio of a decaying exponential (with time constant T 2 ) is a maximum in the presence of thermal noise. While first reported in 1977, interest in this result greatly increased after about the year 2000, when it began to influence thinking in nonuniform sampling, sensitivity, and pulse sequence design. Overall, 1.26 T 2 has become a lens through which to view the evolution of NMR data acquisition and processing. An enduring lesson of the 1.26 T 2 story is the value of describing and analyzing the properties of magnetic resonance signals in the time domain prior to any further spectral analysis and processing, a concept which is at the core of many modern analytic techniques.

David Rovnyak

The past, present, and future of 1.26T2

1.26T2的过去、现在和未来

A summary of the career of Daniel D. Traficante

丹尼尔·D·特拉菲坎特职业生涯概述

An ESR spin probe technique with non‐TEMPO radicals, such as nitronyl nitroxide (NN), benzonitronyl nitroxide (BzNN), and iminonitroxide (IN) radicals, was used for a porous metal‐organic framework (MOF), [(ZnI 2 ) 3 (TPT) 2 ] (ZnTPT; TPT = tris(4‐pyridyl)‐1,3,5‐triazine), at room temperature. The principal values of g and hyperfine coupling ( A ) tensors estimated from spectral reproduction were different from those for organic matrices for some of these radicals. These results indicate that host‐guest interactions occur between the ZnTPT matrix and guest radicals. Thus, when using NN, BzNN, and IN radicals as spin probes for a porous MOF, the interaction between the metal atoms or organic ligands in host materials and guest radicals should be considered. The experimental ESR spectra for the derivatives of NN or BzNN radicals were reproduced only by the rigid‐limit component in the ESR time scale. However, those for the derivatives of IN radicals were approximately reproduced only by rotational diffusion around the z ‐axis perpendicular to the plane in the IN group. Interestingly, this reproduction was not around the y ‐axis of the principal axes of the g tensors, parallel to the molecular long axis, as previously observed in a few organic matrices. The IN radicals dispersed in the ZnTPT matrix are expected to be accommodated in cylindrical or pseudocylindrical nanospaces sandwiched by the pyridyl or triazine rings of TPT in ZnTPT. These findings show that the ESR spin probe technique using non‐TEMPO radicals can be used to investigate the chemical and biological structures of nanosized materials.

Hirokazu Kobayashi

Kento Akiniwa

Fumiyasu Iwahori

Hidehiko Honda

Masato Yamamoto

Electron Spin Resonance Spin Probe Technique for Investigating Non‐TEMPO Radicals Dispersed in Nanospaces of a Crystalline Zn Complex

电子自旋共振自旋探针技术用于研究分散在晶态锌配合物纳米空间中的非TEMPO自由基

Solid-state deuterium NMR is well suited to the study of the conformational dynamics of DNA. Deuterium quadrupole echo spectra for a particular motional model can be calculated and matched to the experimental spectrum to extract information on the DNA dynamics; however, doing so can be very time-intensive. The two-axis motion used to model the dynamics of either 2″ or 5′/5″ furanose ring deuteron is particularly complex with up to ten independent variables that can be optimized. Here, we present a program which automates both the input script generation and searches the parameter space for the best fit using a simulated annealing algorithm. The parameter, <math xmlns="http://www.w3.org/1998/Math/MathML" id="M1"> <msubsup> <mrow> <mi>χ</mi> </mrow> <mrow> <mtext>red</mtext> </mrow> <mrow> <mn>2</mn> </mrow> </msubsup> </math> , provides a relative measure of goodness of fit. This method reduces the overall time to determine the best fit of a line shape to a few days, in most cases, when running on a low-power desktop PC. The automated fitting program presented here can be easily modified to generate input scripts for new models, incorporate a weighting factor to the <math xmlns="http://www.w3.org/1998/Math/MathML" id="M2"> <msubsup> <mrow> <mi>χ</mi> </mrow> <mrow> <mtext>red</mtext> </mrow> <mrow> <mn>2</mn> </mrow> </msubsup> </math> calculation to emphasize key line shape features, or fit nonsymmetrized data. This adaptable program will make simulation of solid-state deuterium spectra accessible to a broader audience.

Kari Pederson

Michael Groves

Gary P. Drobny

Simulated Annealing Method for the Automated Simulation of DNA Dynamics in the HhaI Protein Binding Site

HhaI蛋白结合位点DNA动力学的模拟退火方法自动化模拟

This study was aimed to investigate the application value of magnetic resonance imaging (MRI) scanning examination in the preoperative treatment of functional glioma and to analyze the application effect of nursing intervention in the operating room in the treatment of fiber surgery. In this study, 80 patients with functional glioma were included as research objects and randomly rolled into the control group (routine nursing) and the experimental group (comfort nursing intervention in the operating room), with 40 cases in each group. All patients underwent craniocerebral MRI plain scan plus enhanced scan before surgery. The levels of the heart rate, systolic blood pressure, diastolic blood pressure, interleukin-6 (IL-6), cortisol, and anxiety before and after the intervention in the two groups were compared when patients entered the operating room (T1), when anesthesia took effect (T2), at the end of surgery (T3), when patients regained consciousness after surgery (T4), and 1 day after surgery (T5). MRI showed that the main glioma sites were located in the basal ganglia region (26.25%), followed by the central region (20.00%) and the Broca region (17.5%). The levels of IL-6 at T2, T3, and T4 in the control group were 186.45 ± 64.55 ng/L, 287.68 ± 34.59 ng/L, and 488.69 ± 81.14 ng/L, respectively, which were inferior to those at T2 (167.44 ± 15.59 ng/L), T3 (186.25 ± 52.64 ng/L), and T4 (356.57 ± 48.22 ng/L) in the test group. The SAS score of the test group after intervention (45.38 ± 2.02) was lower than that of the control group (51.03 ± 3.65) ( <math xmlns="http://www.w3.org/1998/Math/MathML" id="M1"> <mi>P</mi> <mo>&lt;</mo> <mn>0.05</mn> </math> ). The levels of cortisol in the test group (T2 (8.89 1.23 ng/L), T3 (9.23 1.25 ng/L), and T4 (11.78 1.27 ng/L) were lower than those in the control group (T2 (11.58 ± 2.48 ng/L), T3 (12.06 ± 2.82 ng/L), and T4 (13.04 ± 11.78)). In short, preoperative MRI scanning was beneficial to detect the location of glioma in functional area. Comfort nursing in the operating room can effectively relieve the anxiety and depression of glioma patients and improve the adverse psychological conditions of the patients.

Tong Shen

Ran Wang

Xin Zhao

Lin Wang

Ying Li

Ting Liu

Comfortable Nursing in the Intraoperative MRI Evaluation Combined with Microsurgery in the Treatment of Functional Area Glioma

功能区胶质瘤治疗中术中MRI评估联合显微手术的舒适护理

To investigate the effects of early nursing intervention on brain injury among premature infants, 100 premature infants diagnosed with brain injury were included in the research and randomly divided into the control group (50 cases) and the experimental group (50 cases). The patients in the two groups were performed with the same conventional comprehensive treatment. The patients in the control group received conventional nursing while those in the experimental group underwent early nursing intervention. During follow-up, neurodevelopment, motor behavior, the incidence rate of brain injury, and nursing satisfaction of the infants in the two groups were compared. It was demonstrated that the five neurodevelopment scores of the experimental group were all higher than those of the control group. The differences showed statistical significance ( <math xmlns="http://www.w3.org/1998/Math/MathML" id="M1"> <mi>P</mi> <mo>&lt;</mo> <mn>0.05</mn> </math> ). The total effective rate of motor development of the experimental group reached 94%, while that of the control group amounted to 80%. Obviously, the total effective rate of motor development of the experimental group was higher than that of the control group. The difference was statistically significant ( <math xmlns="http://www.w3.org/1998/Math/MathML" id="M2"> <mi>P</mi> <mo>&lt;</mo> <mn>0.05</mn> </math> ). The nursing satisfaction of the experimental group reached 98%, which was apparently higher than that of the control group (74%). The difference suggested statistical significance ( <math xmlns="http://www.w3.org/1998/Math/MathML" id="M3"> <mi>P</mi> <mo>&lt;</mo> <mn>0.05</mn> </math> ). The rates of brain injury at 1 and 2 years after the birth of the experimental group were 6% and 2%, respectively. The rates of brain injury at 1 and 2 years after the birth of the control group amounted to 18% and 14%, respectively. The rates of brain injury at 1 and 2 years after the birth of the experimental group were lower than those of the control group. The difference revealed statistical significance ( <math xmlns="http://www.w3.org/1998/Math/MathML" id="M4"> <mi>P</mi> <mo>&lt;</mo> <mn>0.05</mn> </math> ). Hence, the early nursing intervention of premature infants with brain injury could promote brain development, improve neurological function, reduce the incidence of brain injury, and achieve an ideal nursing effect.

Aiyan Liu

Huangai Zhang

Wei Guo

Effect of Early Nursing Intervention under Amplitude-Integrated Electroencephalography and Magnetic Resonance Images on Brain Injury in Premature Infants

早期护理干预在振幅整合脑电图和磁共振图像下对早产儿脑损伤的影响

acBWQ6	Concepts Magnetic Resonance
Journal Impact	0.59
mbqgSu	SPECTROSCOPY(Q4)
xGGr6y	SCI Q4中科院 4 区

ISSN	1546-6086, 1552-5023
h-index	53
hQoIdU	化学(4区)化学物理化学(4区)化学物理原子、分子和化学物理(4区)化学核医学(4区)化学光谱学(4区)

u9zg3I	物理计算机科学材料科学量子力学化学数学核磁共振工程类医学生物有机化学放射科
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Concepts in Magnetic Resonance Part A: Bridging Education and Research

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Density Matrix of Two Spin‐1/2 Particles: Pure and Mixed States

Aging of polymeric materials by stray‐field NMR relaxometry with the NMR ‐ MOUSE

Diffusion measurements using the second echo

The past, present, and future of 1.26T₂

A summary of the career of Daniel D. Traficante

Density Matrix of Two Spin‐1/2 Particles: Pure and Mixed States

Electron Spin Resonance Spin Probe Technique for Investigating Non‐TEMPO Radicals Dispersed in Nanospaces of a Crystalline Zn Complex

Simulated Annealing Method for the Automated Simulation of DNA Dynamics in the HhaI Protein Binding Site

Comfortable Nursing in the Intraoperative MRI Evaluation Combined with Microsurgery in the Treatment of Functional Area Glioma

Effect of Early Nursing Intervention under Amplitude-Integrated Electroencephalography and Magnetic Resonance Images on Brain Injury in Premature Infants