⁸⁹Zr‐Labeled DFO@Durvalumab‐HSA nanoparticles: In vitro potential for triple‐negative breast cancer

2024-10-3

Sm(Ⅲ), Gd(Ⅲ), and Eu(Ⅲ) complexes with 8‐hydroxyquinoline derivatives as potential anticancer agents via inhibiting cell proliferation, blocking cell cycle, and inducing apoptosis in NCI‐H460 cells

2024-10-2

Epigenetic mechanism of EZH2‐mediated histone methylation modification in regulating ferroptosis of alveolar epithelial cells in sepsis‐induced acute lung injury

2024-9-29

Synthesis, anticancer activity and mechanism of action of Fe(III) complexes

2024-9-27

m6A‐activated BACH1 exacerbates ferroptosis by epigenetic suppression HSPB1 in severe acute pancreatitis

2024-9-16

Issue Information

2024-9-16

A new perspective on antiangiogenic antibody drug resistance: Biomarkers, mechanisms, and strategies in malignancies

2024-9-1

Daidzin enhances memory and the antischizophrenia drug olanzapine's effects, possibly through the 5‐HT_2A and D₂ receptor interaction pathways

2024-9-1

Biphenylsulfonamides as effective MMP‐2 inhibitors with promising antileukemic efficacy: Synthesis, in vitro biological evaluation, molecular docking, and MD simulation analysis

2024-9-1

Fasudil attenuates syncytin‐1‐mediated activation of microglia and impairments of motor neurons and motor function in mice

2024-9-1

The mechanism of action and chemical synthesis of FDA newly approved drug molecules

2024-9-1

A thiourea‐bridged ^99mTc(CO)₃‐dipicolylamine‐2‐nitroimidazole complex for targeting tumor hypoxia: Utilizing metabolizable thiourea‐bridge to improve pharmacokinetics

2024-9-1

Starch‐based “smart” nanomicelles: Potential delivery systems for doxorubicin

2024-8-29

Induction of apoptosis by oridonin in nonfunctioning pituitary adenoma cells

2024-8-26

Diphenyl urea‐benzylidene acetohydrazide hybrids as fibroblast growth factor receptor 1 inhibitors and anticancer agents

2024-8-24

Tirbanibulin (KX2‐391) analog KX2‐361 inhibits botulinum neurotoxin serotype A mediated SNAP‐25 cleavage in pre‐ and post‐intoxication models in cells

2024-8-21

Asiaticoside enhances the effect of propofol on the invasion, ferroptosis and immune escape of bladder cancer

2024-8-19

GSTO2 ameliorates human neuroblastoma cell apoptosis, inflammation, ferroptosis, and oxidative stress by upregulating GPX4 expression in intracerebral hemorrhage

2024-8-18

Issue Information

2024-8-17

Assessment of sedative activity of fraxin: In vivo approach along with receptor binding affinity and molecular interaction with GABAergic system

2024-8-17

^99mTc‐labeled, tofacitinib citrate encapsulated chitosan microspheres loaded in situ gel formulations for intra‐articular treatment of rheumatoid arthritis

2024-8-1

Nanovaccines: Immunogenic tumor antigens, targeted delivery, and combination therapy to enhance cancer immunotherapy

2024-8-1

Kynurenine pathway in type 2 diabetes: Role of metformin

2024-8-1

RETRACTION: “Dose‐dependent Chemopreventive Effects of Citronellol in DMBA‐Induced Breast Cancer Among Rats”

2024-8-1

Design, synthesis, molecular modeling, in vitro evaluation of novel piperidine‐containing hydrazone derivatives as cholinesterase inhibitors

2024-8-1

Targeted degradation of KRAS protein in non‐small cell lung cancer: Therapeutic strategies using liposomal PROTACs with enhanced cellular uptake and pharmacokinetic profiles

2024-8-1

Therapeutic effects of tilorone on mammary carcinogenesis through downregulation of pro‐inflammatory cytokines and oxidative stress

2024-8-1

Recombinant human epidermal growth factor‐loaded liposomes and transferosomes for dermal delivery: Development, characterization, and cytotoxicity evaluation

2024-7-23

Design of novel broad‐spectrum antiviral nucleoside analogues using natural bases ring‐opening strategy

2024-7-20

A novel cinnamic and caffeic acid‐conjugated peptide analogs with anticonvulsant and analgesic potency: Comparative analyses of <i>trans/cis</i> isomers

2024-7-20

Antiplasmodial action of 4‐nitrobenzenesulfonamide chalcones: Design, synthesis, characterisation, in vitro and in silico evaluation against blood stages of <i>Plasmodium falciparum</i> 3D7

2024-7-18

Discovery of 5‐(1‐benzyl‐1H‐imidazol‐4‐yl)‐1,2,4‐oxadiazole derivatives as novel RIPK1 inhibitors via structure‐based virtual screening

2024-7-18

Study on the role of MYCN in retinoblastoma by inhibiting p53 and activating wnt/βcatenin/Fra‐1 signaling pathway by reducing DKK3

2024-7-14

Identification of aryl hydrocarbon receptor allosteric antagonists from clinically approved drugs

2024-7-11

Inhibition of the TCF12/VSIG4 axis by palbociclib diminishes the proliferation and migration of glioma cells and decreases the M2 polarization of glioma‐associated microglia

2024-7-5

Preliminary evaluation of antiproliferative and apoptotic activities of novel indolin‐2‐one derivatives

2024-7-3

Novel 1,3,4‐oxadiazole derivatives of naproxen targeting EGFR: Synthesis, molecular docking studies, and cytotoxic evaluation

2024-7-2

Exploring chromone‐2‐carboxamide derivatives for triple‐negative breast cancer targeting EGFR, FGFR3, and VEGF pathways: Design, synthesis, and preclinical insights

2024-7-1

Enriching iPSC research diversity: Harnessing human biobank collections for improved ethnic representation

2024-6-29

Issue Information

2024-6-29

New benzimidazole‐oxadiazole derivatives as potent VEGFR‐2 inhibitors: Synthesis, anticancer evaluation, and docking study

2024-6-1

Vedolizumab in the treatment of Crohn's disease: A promising therapeutic approach

2024-6-1

Oxymatrine attenuates sepsis‐induced inflammation and organ injury via inhibition of HMGB1/RAGE/NF‐κB signaling pathway

2024-6-1

2‐(Methyl(phenyl)amino)‐<i>N</i>‐(phenyloxyphenyl)acetamide structural motif representing a framework for selective SIRT2 inhibition

2024-6-1

Vicinal diaryl pyrazole with tetrazole/urea scaffolds as selective angiotensin converting enzyme‐1/cyclooxygenase‐2 inhibitors: Design, synthesis, anti‐hypertensive, anti‐fibrotic, and anti‐inflammatory

2024-6-1

Downregulation of HIGD1B induces mitochondria‐mediated apoptosis in gastric cancer cells by inactivating Akt and ERK pathways

2024-6-1

SEP‐363856 exerts neuroprotection through the PI3K/AKT/GSK‐3β signaling pathway in a dual‐hit neurodevelopmental model of schizophrenia‐like mice

2024-6-1