Osteogenic effect of an adiponectin-derived short peptide that rebalances bone remodeling: a potential disease-modifying approach for postmenopausal osteoporosis therapy

2024-7-29

Antitumor activity of Polygonatum sibiricum polysaccharides

2024-7-26

Pentacyclic triterpenes, potential novel therapeutic approaches for cardiovascular diseases

2024-7-24

Dual roles of myeloid-derived suppressor cells in various diseases: a review

2024-7-15

Implications of inflammatory cell death-PANoptosis in health and disease

2024-7-10

Dihydroartemisinin inhibits follicular helper T and B cells: implications for systemic lupus erythematosus treatment

2024-7-8

C-phycocyanin reinforces autophagy to block pulmonary fibrogenesis by inhibiting lncIAPF biogenesis

2024-7-1

E3 ubiquitin ligase RNF180 mediates the ALKBH5/SMARCA5 axis to promote colon inflammation and Th17/Treg imbalance in ulcerative colitis mice

2024-7-1

Correction: Antibody drug conjugates as targeted cancer therapy: past development, present challenges and future opportunities

2024-6-26

Challenges and opportunities of developing small-molecule therapies for age-related macular degeneration

2024-6-20

Interplay between YAP/TAZ and metabolic dysfunction-associated steatotic liver disease progression

2024-6-1

Antibacterial properties of natural products from marine fungi reported between 2012 and 2023: a review

2024-6-1

Exploring molecular mechanisms, therapeutic strategies, and clinical manifestations of Huntington’s disease

2024-5-19

Continuous TNF-α exposure in mammary epithelial cells promotes cancer phenotype acquisition via EGFR/TNFR2 activation

2024-5-1

Phytochemical and pharmacological properties of the genus Tamarix: a comprehensive review

2024-5-1

Potential of natural products in inflammation: biological activities, structure–activity relationships, and mechanistic targets

2024-5-1

PBPK modeling to predict the pharmacokinetics of venlafaxine and its active metabolite in different CYP2D6 genotypes and drug–drug interactions with clarithromycin and paroxetine

2024-4-25

Combination therapy involving HSP90 inhibitors for combating cancer: an overview of clinical and preclinical progress

2024-4-17

Potential biological functions and future perspectives of sialylated milk oligosaccharides

2024-4-1

TNF receptor 2 knockout mouse had reduced lung cancer growth and schizophrenia-like behavior through a decrease in TrkB-dependent BDNF level

2024-4-1

Advances in sarcopenia: mechanisms, therapeutic targets, and intervention strategies

2024-4-1

The novel psychoactive substance 25E-NBOMe induces reward-related behaviors via dopamine D1 receptor signaling in male rodents

2024-3-29

Indole-3-acetic acid ameliorates dextran sulfate sodium-induced colitis via the ERK signaling pathway

2024-3-15

The potential of therapeutic strategies targeting mitochondrial biogenesis for the treatment of insulin resistance and type 2 diabetes mellitus

2024-3-1

Astragali Radix: comprehensive review of its botany, phytochemistry, pharmacology and clinical application

2024-3-1

New autophagy-modulating lanostane-type triterpenoids from a hallucinogenic poisonous mushroom Gymnopilus orientispectabilis

2024-2-28

Prenylated flavonoid fractions from Glycyrrhiza glabra alleviate insulin resistance in HepG2 cells by regulating the ERK/IRS-1 and PI3K/Akt signaling pathways

2024-1-24

Herbal medicine and gut microbiota: exploring untapped therapeutic potential in neurodegenerative disease management

2024-1-15

Comparative metabolism of aschantin in human and animal hepatocytes

2024-1-5

Physiologically based pharmacokinetic (PBPK) modeling of pitavastatin in relation to SLCO1B1 genetic polymorphism

2023-12-30

Antibody-drug conjugates in cancer therapy: innovations, challenges, and future directions

2023-12-28

Dysregulation of histone deacetylases in ocular diseases

2023-12-27

Gastric cancer and mesenchymal stem cell-derived exosomes: from pro-tumorigenic effects to anti-cancer vehicles

2023-12-27

PBPK modeling to predict the pharmacokinetics of pantoprazole in different CYP2C19 genotypes

2023-12-27

Arsenic trioxide: applications, mechanisms of action, toxicity and rescue strategies to date

2023-12-26

The PIN1-YTHDF1 axis promotes breast tumorigenesis via the m6A-dependent stabilization of AURKA mRNA

2023-12-26

Role of monocarboxylate transporter I/lactate dehydrogenase B-mediated lactate recycling in tamoxifen-resistant breast cancer cells

2023-12-1

Physiologically based pharmacokinetic (PBPK) modeling to predict the pharmacokinetics of irbesartan in different CYP2C9 genotypes

2023-12-1

Targeting dysregulated lipid metabolism in the tumor microenvironment

2023-12-1

Phytochemistry and pharmacology of plants in the genus Chaenomeles

2023-12-1

Selumetinib overcomes gefitinib primary and acquired resistance by regulating MIG6/STAT3 in NSCLC

2023-11-30

Human milk oligosaccharides 3′-sialyllactose and 6′-sialyllactose attenuate LPS-induced lung injury by inhibiting STAT1 and NF-κB signaling pathways

2023-11-9

Death-associated protein kinase 1 phosphorylates MDM2 and inhibits its protein stability and function

2023-10-7

2-Geranyl-1-methoxyerythrabyssin II alleviates lipid accumulation and inflammation in hepatocytes through AMPK activation and AKT inhibition

2023-10-1

Exploring new histone deacetylase 6 inhibitors and their effects on reversing the α-tubulin deacetylation and cell morphology changes caused by methamphetamine

2023-9-30

Artemongolins A–K, undescribed germacrane-guaiane sesquiterpenoid dimers from Artemisia mongolica and their antihepatoma activities

2023-9-28

Anti-osteoporosis effects of triterpenoids from the fruit of sea buckthorn (Hippophae rhamnoides) through the promotion of osteoblast differentiation in mesenchymal stem cells, C3H10T1/2

2023-9-26

Multifaceted roles of mitochondrial dysfunction in diseases: from powerhouses to saboteurs

2023-9-26

Review on pharmacological effects of gastrodin

2023-9-25

Androgen receptor and hyaluronan-mediated motility receptor as new molecular targets of baicalein: new molecular mechanisms for its anticancer properties

2023-8-1