Therapeutic Advances in Ophthalmology

Congenital aniridia is a rare genetic eye disorder often associated with PAX6 gene mutations, leading to complex ocular manifestations, including aniridia-associated keratopathy (AAK) and cataracts. The surgical management of cataracts in these patients is particularly challenging due to severe corneal opacities, which obscure key surgical steps such as capsulorhexis and phacoemulsification. This report presents two cases of congenital aniridia with severe AAK, in which chandelier retroillumination-assisted cataract surgery was employed. This technique, typically used in vitreous surgery, provided enhanced visualization of the lens through posterior segment illumination, facilitating successful cataract extraction and intraocular lens implantation. Both patients showed significant postoperative improvement in visual acuity. These cases demonstrate the feasibility and effectiveness of chandelier retroillumination-assisted cataract surgery in patients with congenital aniridia complicated by severe corneal opacity.

Joseph Hu

Chao-Chien Hu

Chandelier retroillumination-assisted cataract surgery in two cases of congenital aniridia with severe aniridia-associated keratopathy: case series

先天性无虹膜伴严重无虹膜相关角膜病变两例：吊灯式反向照明辅助白内障手术病例系列

Managing recurrent pterygium combined with symblepharon presents significant challenges in ophthalmology. Clinicians aim to reconstruct the ocular surface, alleviate eye movement restrictions, and minimize recurrence risks.

Huixiang Ma

Jiahui Shen

Xuhao Chen

Xianfeng Ye

Shuxia Xu

Zongduan Zhang

The efficacy and safety of continuous blanket suture for severe recurrent pterygium with symblepharon

连续毯式缝合治疗伴有睑球粘连的复发性重症翼状胬肉的疗效与安全性

Background: Allergic conjunctivitis is a prevalent ocular condition characterized by inflammation of the conjunctiva due to hypersensitivity reactions to various allergens. Understanding its epidemiology and clinical characteristics is crucial for effective management and public health interventions. Methods: This cross-sectional study investigated the prevalence, triggers, and associated factors of allergic conjunctivitis among residents of the Southern region of Saudi Arabia. Data were collected using a structured questionnaire administered through Google Forms. Statistical analysis was performed using IBM SPSS, including descriptive statistics and bivariable/multivariable analyses. Results: A total of 693 participants were recruited through convenience sampling via online platforms. Among the participants, 73.9% reported ocular symptoms, while 26.1% did not. Dust emerged as the most common trigger for ocular symptoms (32.9%), followed by eye drops/contact lenses (8.7%), animal dander (6.9%), and chemicals (5.8%). Notably, 39.7% reported experiencing ocular symptoms throughout the year. Despite the prevalence of ocular symptoms, only 26.7% consulted an ophthalmologist. Multivariable analysis revealed that gender and seasonal variation in symptoms were associated with allergic conjunctivitis diagnosis. Females showed a lower odds ratio (OR) of being diagnosed with allergic conjunctivitis compared to males (OR: 0.62, 95% CI: 0.29–1.31), and participants experiencing symptoms with no specific season had significantly lower odds of being diagnosed with allergic conjunctivitis (OR: 0.28, 95% CI: 0.11–0.72). A history of allergic rhinitis demonstrated a strong positive association with allergic conjunctivitis diagnosis (OR: 3.77, 95% CI: 1.83–7.75). Conclusion: The study highlights the considerable burden of allergic conjunctivitis and the underutilization of healthcare services among affected individuals in the Southern region of Saudi Arabia. Tailored interventions and increased awareness are essential for effective management and mitigation of allergic conjunctivitis’s impact on affected individuals and healthcare systems.

Waleed ALDhabaan

Saleh Ghulaysi

Albatool Alqahtani

Eman Hurissi

Manar M. Alamri

Almuhannad G. Alnami

Ahmed H. Sumayli

Yahya A. Dhamri

Amani A. Mosleh

Ethar A. Khawaji

Abdullah A. Alshahrani

Abdulsalam S. Alfaifi

Saja M. Alghamdi

Clinical characteristics of allergic conjunctivitis in the Southern region of Saudi Arabia: a cross-sectional study

沙特阿拉伯南部地区过敏性结膜炎的临床特征：一项横断面研究

Charles Bonnet syndrome (CBS) refers to the presence of visual hallucinations experienced by people, without cognitive, or psychiatric deficits that are related to sight loss. This study surveyed younger adults (18-60 years) with visual impairments, to assess the impact of anxiety, depression, loneliness, and the COVID-19 lockdowns on their visual hallucinations.

Robin Walker

Caecilie Valla Broman

Sam Hopkins

Mark Gould

Juliet Holdstock

Are depression, anxiety and loneliness associated with visual hallucinations in younger adults with Charles Bonnet syndrome?

抑郁症、焦虑和孤独与查尔斯·邦纳综合征年轻患者的视幻觉有关吗？

Charles Bonnet syndrome (CBS) refers to the experience of visual hallucinations occurring secondary to sight loss. Although there is an increasing amount of research on this phenomenon, CBS remains a lesser-known outcome of visual impairment, with limited research into the impact on the patient.

Sonali Dave

Lee Jones

Matthew Lee

Lara Ditzel-Finn

Claire Castle

Nikki Heinze

Judith Potts

Mariya Moosajee

Renata S. M. Gomes

The experiences of visually impaired military veterans with Charles Bonnet syndrome

视觉障碍退伍军人与邦纳综合征的体验

Abbreviation	Ophthalmol Eye Dis
Journal Impact	2.46
Quartiles(Global)	OPHTHALMOLOGY(Q2)

ISSN	2515-8414
h-index	19

Publication Information	Publisher: SAGE Publications Ltd，Publishing cycle: ，Journal Type: journal，Open Access Journals: Yes
Basic data	Year of publication: 2018，Proportion of original research papers: 65.91%，Self Citation Rate:0.00%， Gold OA Rate: 95.71%
Journal Fees	$2650Details
Average review cycle	网友分享经验：12 Weeks

Therapeutic Advances in Ophthalmology

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Chandelier retroillumination-assisted cataract surgery in two cases of congenital aniridia with severe aniridia-associated keratopathy: case series

The efficacy and safety of continuous blanket suture for severe recurrent pterygium with symblepharon

Clinical characteristics of allergic conjunctivitis in the Southern region of Saudi Arabia: a cross-sectional study

Are depression, anxiety and loneliness associated with visual hallucinations in younger adults with Charles Bonnet syndrome?

The experiences of visually impaired military veterans with Charles Bonnet syndrome

Chandelier retroillumination-assisted cataract surgery in two cases of congenital aniridia with severe aniridia-associated keratopathy: case series

The efficacy and safety of continuous blanket suture for severe recurrent pterygium with symblepharon

Clinical characteristics of allergic conjunctivitis in the Southern region of Saudi Arabia: a cross-sectional study

Are depression, anxiety and loneliness associated with visual hallucinations in younger adults with Charles Bonnet syndrome?

The experiences of visually impaired military veterans with Charles Bonnet syndrome