Chinese Journal of Integrated Traditional and Western Medicine

To assess whether adjuvant Chinese patent medicines (CPMs) to standard treatment could reduce recurrent bleeding after variceal bleeding in cirrhotic patients.

Qun Zhang

Yu-Xin Li

Yao Liu

Yi-Xin Hou

Bing-Bing Zhu

Yun-Yi Huang

Ke Shi

Xian-Bo Wang

Chinese journal of integrative medicine

Chin J Integr Med

Effects of Adjuvant Chinese Patent Medicine Therapy on Prevention of Variceal Rebleeding: A Retrospective Cohort Study.

中药辅助治疗对预防食管静脉曲张再出血的影响：一项回顾性队列研究。

To investigate the efficacy of integrated Chinese and Western medicine extending the progression-free survival (PFS) and overall survival (OS) of limited-stage small cell lung cancer (LS-SCLC) patients after the first-line chemoradiotherapy.

Run-Zhi Qi

Shu-Lin He

Yue Li

Yu-Wei Zhao

Liang Geng

Jie He

Meng-Qi Cheng

Jia-Qi Hu

Cong-Huang Li

Bao-Jin Hua

Retrospective Clinical Study on Integrated Chinese and Western Medicine in Treatment of Limited-Stage Small Cell Lung Cancer.

中西医结合治疗局限期小细胞肺癌的回顾性临床研究

Cholangiocarcinoma (CCA) is a malignant tumor originating from cholangiocytes. However, it remains unclear about the pathogenesis of this carcinoma, which may be related to multiple factors. Currently, CCA is mainly treated by surgery, chemotherapy, and radiotherapy. Among them, surgery is the only potentially curative option for CCA. Nevertheless, the high malignancy and asymptomatic nature of CCA may lead to poor treatment outcomes. It has been demonstrated that Chinese medicine (CM) plays a significant role in various antitumor applications. Meanwhile, CM exhibits fewer side effects and high availability. Moreover, the in vitro application of CM monomers has been explored in many domestic and foreign studies. This article mainly reviews the signaling pathways and molecular mechanisms of CM monomers in the treatment of CCA in recent years. These findings are expected to provide new insights into the treatment of CCA.

Xiang Wang

Xiao-qing Wang

Kai Luo

He Bai

Jia-lin Qi

Gui-xin Zhang

Chinese Journal of Integrative Medicine

Research Progress of Chinese Medicine Monomers in Treatment of Cholangiocarcinoma

中药单体治疗胆管癌的研究进展

DNA technology based molecular profiling provides the ultimate and definitive means of authentication for Chinese drugs. RFLP, RP-PCR and microsatellite-SSR examine the whole genome. With the appropriate primer, it is in principle possible to differentiate closely related species and even one individual from another. PCR-SR, PCR-RFLP, AFLP, SCAR, DALP and DNA sequencing examine a defined region on the genome and produce well-defined conclusions. Since different regions on the genome evolve to different extents, by choosing the target DNA carefully, organisms of different systematic levels can be compared. Of these molecular techniques mentioned above, genomic fingerprints and DNA sequences are equally successful in identification of Chinese drugs. Although RFLP, RP-PCR methods do not require prior to genetic background of the genome and can detect DNA polymorphism, the reliability of these fingerprint results can be greatly influenced by experimental conditions. DNA sequencing method focuses on a defined locus on the genome and may provide a definitive means for authentication of Chinese drugs. We, therefore, conclude that it is essential to combine genomic fingerprinting with DNA sequencing analysis in order to increase the accuracy of quality control.

Hui Cao

Yuping Liu

Komatsu Katsuko

But Paul Pui-Hay

Shaw Pang-Chui

DNA Molecular profiling: a new approach to quality control of chinese drugs

DNA分子谱分析：中药质量控制的新方法

To explore the clinical therapeutic effect of Qianggan Capsule (QGC) in treating chronic hepatitis B with liver fibrosis from the pathological aspect. Sixty-three patients of chronic hepatitis B with liver fibrosis were randomly divided into the treated group (n=45) and the control group (n=18). Both groups were treated with general liver protective drugs, such as Glucurone and vitamins B complex for 6 months. To the treated group, QGC was used additionally. The levels of serum alanine transaminase and liver fibrosis indexes including hyaluronic acid (HA), collagen type IV (C-IV) and laminin (LN) as well as the pathological examination of liver biopsy were observed before and after treatment. The liver cirrhosis indexes, HA, C-IV and LN, were improved significantly in the treated group after treatment,P<0.05. The liver function improvement rate in the treated group and the control group was 90.3% and 66.7% respectively, comparison of the two groups showed insignificant difference,P>0.05. Pathological examination showed that the effective rate of treatment on liver inflammatory necrosis activity grade in the treated group was 57. 8% and that on liver fibrosis stage was 75. 6%, which were significantly improved as compared with those before treatment (P<0.05 andP<0.01), while in the control group, no significant improvement was found after treatment (P>0.05) QGC has marked effects in reversing liver fibrosis and alleviating hepatic inflammatory necrosis in patients of chronic hepatitis B with liver fibrosis, and could lower the serum liver fibrosis related indexes effectively.

Liu-ming Yang

Yan-long Zhao

Wu Zhi-rong

Chen Du-fang

Chen Zhuo-ying

Xu Ke-cheng

Zuo Jian-sheng

Zuo Bei-hai

Zhang Wan-dai

Clinical pathologic study on effect of Qianggan capsule in treating patients of chronic hepatitis B with liver cirrhosis

强肝胶囊治疗慢性乙型肝炎肝硬化患者的临床病理研究

Yu-qing Chen

Yan-xian Zhang

Xu Zhang

Yong-mei Lyu

Zeng-li Miao

Xiao-yu Liu

Xu-chu Duan

Mechanism and Application of Chinese Herb Medicine in Treatment of Peripheral Nerve Injury

中药治疗周围神经损伤的机制与应用

Zi-hao Liu

Wen-long Xing

Hong-xu Liu

Ju-ju Shang

Ai-yong Li

Qi Zhou

Zhen-min Zhang

Zhi-bao Li

Ke-ji Chen

Effect of Kuanxiong Aerosol on Perioperative Coronary Microcirculation in Patients with Unstable Angina Undergoing Elective PCI: A Pilot Randomized Controlled Trial

宽胸气雾剂对择期PCI不稳定型心绞痛患者围手术期冠状微循环的影响：一项初步随机对照试验

To explore the role of the natural compound hesperidin in glycolysis, the key ratelimiting enzyme, in colorectal cancer (CRC) cell lines.

Ke-xiang Sun

Wei-shan Tan

Hao-yue Wang

Jia-min Gao

Shu-yun Wang

Man-li Xie

Wan-li Deng

Hesperidin Suppressed Colorectal Cancer through Inhibition of Glycolysis

橙皮苷通过抑制糖酵解抑制结直肠癌

To entrap carvacrol (CAR) in bovine serum albumin nanoparticles (BSANPs) to form CAR-loaded BSANPs (CAR@BSANPs) and to explore the anti-cancer effects in breast adenocarcinoma cells (MCF-7 cells) treated with CAR and CAR@BSANPs.

Pouria Khodavandi

Neda Karami

Alireza Khodavandi

Fahimeh Alizadeh

Esmaeel Panahi Kokhdan

Ahmad Zaheri

Probable Molecular Targeting of Inhibitory Effect of Carvacrol-Loaded Bovine Serum Albumin Nanoparticles on Human Breast Adenocarcinoma Cells

牛血清白蛋白纳米粒负载香芹酚对人乳腺癌腺癌细胞抑制作用的潜在分子靶向

To evaluate the efficacy and safety of Chinese medicine (CM) Zihua Wenfei Zhisou Granule (ZWZG) in postinfectious cough (PIC) patients with CM syndrome of wind-cold invading Fei (Lung, WCIF).

Ting Li

Xue-Mei Liu

Mei Yang

Yan-Qing Wu

Wei Liu

Bing Mao

Hong-Li Jiang

Efficacy and Safety of Zihua Wenfei Zhisou Granule in Treatment of Postinfectious Cough: A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase II Clinical Trial

梓花温肺止嗽颗粒治疗感染后咳嗽的疗效与安全性：一项多中心、随机、双盲、安慰剂对照的II期临床试验

Publication Information	Publisher: Chinese Association of the Integration of Traditional and Western Medicine, China Academy of Traditional Chinese Medicine，Publishing cycle: ，Journal Type: journal，Open Access Journals: No
Basic data	Year of publication: 1995，Proportion of original research papers: ，Self Citation Rate:， Gold OA Rate:

Chinese Journal of Integrated Traditional and Western Medicine

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