Pharmacognosy Reviews

Black cumin (Nigella sativa) is a well-known medicinal plant and the most exhaustively exploited species of Ranunculaceae family. Nigella sativa seeds have been extensively used as spice in Middle Eastern and Indian cuisine. In addition, they have a long history of use in medicine. This review described the pharmacognostical characteristics, traditional applications and health benefits of N. sativa. The review also described the phytochemical composition and pharmacological properties of N. sativa and its bioactive constituents, in particular thymoquinone, the most abundant active constituent responsible of the effectiveness and pharmacological properties of N. sativa. The review also enumerates pharmacokinetics, possible interaction caused by co-administered drugs, daily dose consumption and toxicity of this medicinal plant. These make the use of N. sativa an interesting approach to the development of new adjuvant or complement treatment.

Jean Noël Nyemb

Hazem Shaheen

Lamiaa Wasef

Richard Nyamota

Narimane Segueni

Gaber El-Saber Batiha

Pharmacognosy Reviews/Bioinformatics Trends/Pharmacognosy review

Black Cumin: A Review of its Pharmacological Effects and its Main Active Constituent

黑孜然: 其药理作用及其主要活性成分综述

The plant genus Mucuna comes from the family Fabaceae, subfamily Papilionaceae. At present, about 100 species of climbing shrubs of the genus Mucuna have been found, among which Mucuna pruriens and Mucuna urens stand out, due to the large number of pharmacological properties they possess. We sought to exemplify some of the most important uses, as well as pharmacological and nutritional properties that have been found over the years in Mucuna urens and Mucuna pruriens. Plants of the genus Mucuna have been used in various areas worldwide because they possess a large number of phytoconstituents that give them multiple properties. These plants have stood out for their nutritional value, their antioxidant activity, and their properties to treat various pathologies.

María Celeste Ortega Monge

María Fernanda Rojas Salas

Marianela Chavarría-Rojas

Gustavo Carazo Berrocal

German Madrigal Redondo

Universal Aspects of the Genus Mucuna and the Properties Describe of Mucuna urens and Mucuna pruriens

豆科植物木豆属的普遍特征及其两种植物木豆和木豆的特性描述

Ayapana triplinervis is a plant species widely used in healing processes and in mystical-religious rituals by traditional communities in South America, Africa and Asia. This study aims to make a systematic review of the ethnopharmacological employment, secondary metabolites and biological activity reported in the scientific literature for A. triplinervis. The systematic literature review included scientific articles and theses published between 1987 and 2021 in Google Scholar, Science Direct, Pubmed, Web of Knowledge and CAPES Periodicals databases in English, Portuguese and Spanish. The results indicated that A. triplinervis is chemodiverse in coumarins and validated the ethnopharmacological action cited by traditional communities as antiviral, antinociceptive, antiulcerative, anxiolytic, biocidal activities by in vitro and in vivo biological tests.

Alex Bruno Lobato Rodrigues

Jonathan Lopes de Matos

Rosany Lopes Martins

Érica de Menezes Ra

Lethicia Barreto Brandão

Lizandra Lima Santos

Cleidjane Gomes Faustino

Fábio Rodrigues de Oliveira

Sheylla Susan Moreira da Silva de Almeida

Ethnopharmacological Use, Secondary Metabolites and Biological Activity of Ayapana triplinervis (VAHL) R. M. King and H. Rob.: A Systematic Review

民族药理学应用、次生代谢物及Ayapana triplinervis (VAHL) R. M. King和H. Rob.的生物活性：系统综述

Edible vaccines are created from transgenic plants and animals and contain immunostimulant. Edible vaccines, to put it simply, are medications generated from plants or animals. In underdeveloped countries, oral vaccines are less expensive and more widely available. Researchers came up with the idea of edible vaccines, in which edible plant pieces are employed as a vaccine factory. To make edible vaccinations, scientists put desired genes into plants and then force the plants to generate the proteins expressed in the genes. Transgenic plants are the result of transformation, whereas transformation is the act of converting plants. The edible vaccination promotes mucosal immunity. Dendritic cells in the gut can assist native T cells activate and differentiate into follicular T-helpers (Tfh). T and B cells will respond precisely to a reliable, digestible immunization. Potato, tomato, banana, carrots, tobacco, papaya, algae, and a variety of other plants are utilised as alternative agents for standard vaccinations. Malaria, cholera, hepatitis, rabies, measles, rotavirus, diarrhoea cancer treatments and treatment of covid-19 are among the illnesses for which plant-based vaccines have been created. It takes time and dedication to develop and sell edible vaccinations. Many edible vaccines for animal and human ailments have been developed and have gone through various levels of clinical testing. The importance of plant-based vaccinations is emphasized in this article.

Prancy Patel

Riya Patel

Shivani Patel

Yukta Patel

Manan Patel

Riddhi Trivedi

Edible Vaccines: A Nutritional Substitute for Traditional Immunization

食用疫苗：传统免疫的营养替代品

Because skin aging is so important in terms of looks, research into preventive and therapeutic treatments has proliferated. Ultraviolet (UV) radiation alters the extracellular matrix (ECM), stimulates matrix metalloproteinases (MMPs), while diminishes the elastin and collagen. MMPs are zinc-containing endo-peptidases that help to restore the ECM. The MMP families, based on substrate structure and specificity are: a) collagenases b) gelatinases c) stromelysins d) matrilysins and e) membrane type MMPs. Except for matrilysin, these enzymes contains haemopexin, propeptide and catalytic domains. Among the photoprotective strategies used to prevent and/or treat photoaging are topical sunscreens that work at the molecular level. We investigate photoaging mechanisms and plant bioactives. Skin photoaging is primarily caused by UV radiation from the sun, as it produces reactive oxygen species and disrupt DNA/cellular equilibrium, alter signal transduction pathways and inflammatory cascades, as well as immunosuppression and ECM restoration. Antiaging studies recently predicted the usage of natural chemicals from ancient civilizations. The sun protection factor and antioxidant properties of plants help prevent wrinkles and give the skin a youthful glow. Thus, the current study focuses on the development of anti-photoaging therapies that target specific MMPs connected to skin aging and wrinkle generation. We explored MMP suppressors or inhibitors found in plants.

Madhuri Baghel

Hemant Badwaik

Sangeeta Patil

Azajuddin Azajuddin

Plant Bioactives as Inhibitors of Matrix Metalloproteases and their Anti-skin Photoaging Potential

植物生物活性物质作为基质金属蛋白酶抑制剂及其抗皮肤光老化潜力

Plants have been utilized for the treatment of various diseases since ages because of their plethora of pharmacological actions and almost inferior side effects. Among all medicinal plants seas buckthorn also came into limelight because of its unique appearance and valuable phytoconstituents as well as medicinal properties. The sea buckthorn known as Hippophae rhamnoides L. belonging to family Elaeagnaceae is a berries bearing plant. This review explores the plant profile, phytochemistry, pharmacological activities including: in vivo, in vitro, clinical studies of the plant and market preparation till date of sea buckthorn. The data was collected by comprehensively searching various scientific search engines i.e., PubMed, Google Scholar, web of science etc. According to literature plant contains various phenolic and non-phenolic secondary metabolites and nutrients. Majorly plants contains Carotenoids, Triterpenoids, Phenolic compounds i.e. Kaempferol, quercetin, gallic acid, Catechin, Epicatechin, Gallo catechin etc. Apart from these different parts of the plants also contains Lipids, Proteins, fatty acids, sterols; volatile compounds, Amino acids, Proteins, Sugars, Pectin, Vitamins (C, E, B, K1, D, A, folic acid) Macro and trace elements (potassium, magnesium, calcium, iron, sodium, manganese, zinc, copper, nickel). Sea buckthorn is known for its antioxidant, anti-cancer, antidiabetic, hepatoprotective, wound healing, anti-bacterial, anti-viral etc. pharmacological properties. In conclusion, the elaborate tapestry of sea buckthorn's phytochemistry and its multifaceted pharmacological actions has illuminated a promising path for both nutritional and therapeutic exploration. However, the paper's identification of substantial data gaps will spur more research and development, particularly for the creation of nutraceuticals and herbal medicines based on sea buckthorn.

Surya Prakash

Hurmat Hurmat

Sangita Yadav

Phytochemistry, Pharmacological Actions and Market Formulations of Sea buckthorn (Hippophae rhamnoides L.): A Comprehensive Review

沙棘（Hippophae rhamnoides L.）的植物化学成分、药理作用及市场制剂：综合评述

In recent years, there has been a resurgence of interest in traditional medicinal plants, driven by growing concerns about the side effects of synthetic medicines and the increasing burden of chronic diseases. The comprehensive reviews of various medicinal plants, including Sea buckthorn, Guava, selected traditional medicinal plants, Withania coagulans, and Desmodium canum, highlight the vast potential of these natural resources in modern medicine. However, despite the promising pharmacological actions and medicinal properties of these plants, their full potential remains untapped due to a lack of standardization and promotion of herbal extracts. In this editorial, I argue that standardization and promotion of herbal extracts are crucial for unlocking the power of traditional medicinal plants and ensuring their safe and effective use in modern medicine. Read More . . .

Mueen Ahmed KK

Unlocking the Power of Traditional Medicinal Plants: The Need for Standardization and Promotion of Herbal Extracts

解锁传统药用植物的力量：标准化和推广草药提取物的必要性

Ashwagandha, a renowned medicinal plant within the AYUSH (Ayurveda, Yoga, Unani, Siddha, Homeopathy) System, stands as a plant of paramount significance due to its multifaceted health benefits. Recognizing its pivotal role, the AYUSH Ministry, Delhi's National Medicinal Plants Board (NMPB) launched the "Ashwagandha - A Health Promoter" campaign in the year 2022. This initiative signifies the plant's potential in promoting health and well-being. This comprehensive review endeavours to elucidate various facets of Ashwagandha, encompassing pharmacognosy, phytochemistry, conservation strategies, cultivation practices, therapeutic applications, market dynamics, exploration of value-added products and an overview of current research endeavours.

Sharada Laxman Deore

Bhushan Arun Baviskar

Somshekhar Khadabadi

Anjali Ashok Kide

Ram Chhatrapati Vighne

Ashwagandha-Withania somnifera for Sustainable Socioeconomic Empowerment

南非醉茄-睡茄属植物在可持续社会经济赋权中的作用

Kemmoy Lattibeaudiere

Shannon Newman

A Review of the Multifaceted Plant, Desmodium canum: The Traditional and Ethnopharmacological Applications and its Potential Use in Medicine

多面植物山蚂蝗的综述：传统与民族药理学应用及其在医药中的潜在用途

Ayurveda-The ancient science of life, is a traditional system of medicine originated and evolved in Indian sub-continent. It majorly utilises plant derivatives for the accomplishment of its main aim "Arogya" (health). The 21st century witnessed a huge advancement quality of life in humans due to the revolutionary upliftment in technology. But still 80% of world's total population depends on herbal based medicines and therapies for primary health care. Owing to the high demand and rapid deforestation because of industrialisation, availability of authentic raw drugs for the herbal medicine industry is declining rapidly. "Dasamoola" is an important group of drugs in Ayurveda, in which root of ten drugs are collected and used together. Modern herbal industry utilises an array of physico-chemical techniques to ensure the authenticity, quality and purity of raw drugs. But still gross morphological examination plays a major role in drug identification. This study aims to collect and document authentic samples and to consolidate the important organoleptic features of "Dasamoola." This study will provide insight to some unique identification features of each drug like faint aromatic odour of Agnimantha root, extremely porous and light weight of Patala root etc.

Asha S Raj

Sara Monsy Oommen

Shincymol V V

A Detailed Evaluation on External Morphology of Raw Drug Samples of “Dasamoola”-Ten Roots in Ayurveda

阿育吠陀中“十根”生药样本外部形态的详细评估

Publication Information	Publisher: Wolters Kluwer Medknow Publications，Publishing cycle: ，Journal Type: journal，Open Access Journals: No
Basic data	Year of publication: 2009，Proportion of original research papers: ，Self Citation Rate:， Gold OA Rate:

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