British Journal of Tuberculosis and Diseases of the Chest

J.W. Fraser

Br J Tuberc Dis Chest

Significant primary pulmonary tuberculosis in young contacts

年轻人群中显著的原发性肺结核接触者

Summary A case of pulmonary arteriovenous aneurysm in hereditary telangiectasia is reported. The frequent association of these conditions is stressed with reference to the literature on the subject.

D. Revill

S.G. Flavell Matts

Pulmonary arteriovenous aneurysm in hereditary telangiectasia

遗传性毛细血管扩张症中的肺动静脉瘤

Sixty-seven thymic tumours are classified histologically into epithelial, lymphoid and teratomatous groups. The epithelial tumours, forming approximately 80 per cent. of the series, are further subdivided into differentiated, oval- and spindle-celled, lympho-epitheliomatous, granulomatous and undifferentiated types. An account is given of the distinctive histological features and the clinical course described of each of these types of tumour. It is found that once the histology of the neoplasm is known it is possible to give a guide as to the probable outcome and behaviour of the tumour.

A.D. Thomson

A.C. Thackray

Histology and behaviour of thymic tumours

胸腺肿瘤的组织学与行为

One case of primary neurilemmoma of the left leaf of the diaphragm occurring in a girl aged 5 is described. This brings the total number of primary neurogenic tumours of the diaphragm in the literature to six. This is the second case of neurilemmoma. The presenting feature of this case was severe hypertrophic pulmonary osteoarthropathy. This has occurred in half the cases reported. The removal of the tumour led to rapid improvement in the osteoarthropathy. The importance of early operative treatment is emphasised because of the high incidence of malignancy.

S.A. Trivedi

Neurilemmoma of the diaphragm causing severe hypertrophic pulmonary osteoarthropathy

膈神经鞘瘤引起严重肥厚性肺性骨关节病

A series of 286 cases of pulmonary neoplasm, undergoing surgical treatment, has been investigated to determine the incidence and ˦tiology of disturbances of cardiac rhythm. Fifty-nine patients, or 20·6 per cent., developed ectopic rhythms, all of which were supraventricular in type. Auricular fibrillation was the commonest arrhythmia occurring in 41 patients (70 per cent.). Auricular fibrillation and flutter together accounted for 52 (88 per cent.) of the total of 59 arrhythmias. Most occurred in the first post-operative week (85 per cent.) and all within two weeks. The average duration was four days. In 2 patients death was directly attributed to the arrhythmia. Permanent arrhythmia developed in only 2 patients, both of whom had paroxysms of auricular fibrillation before operation. The main factors of ˦tiological importance were pre-operative cardiovascular disorders, particularly rhythm and conduction disturbances, and various post-operative complications causing anoxia and vagal reflexes. The management and prevention of the rhythm disorders is discussed.

E.J. Epstein

Arrhythmias complicating the surgical treatment of lung carcinoma

肺癌手术治疗中并发的节律失常

Although several enzymes have previously been tried therapeutically, cerase is the first to show definite antibacterial effect. Low toxicity and highly specific antibacterial activity facilitate clinical research, and the apparent anti-tuberculous activity in both animal and human cases justifies larger scale clinical trials, which are in progress. Besides bibliographical data, this article contains information about the pharmacological properties of cerase, and preliminary observations on its use in the treatment of human tuberculosis.

Mahmoud Kamal Muftic

Advances in the pharmacological study of cerase—A new anti-tuberculous agent

cerase药理学研究进展——一种新型抗结核药物

A case is recorded of renal damage, fever and drug rash following twice weekly viomycin treatment. At post-mortem the renal tubules showed necrosis.

R.G. Benians

C.J. Pinto

A fatal case of viomycin hypersensitivity

一种致命的紫霉素超敏反应病例

This paper is a review of patients with pulmonary tuberculosis at the Toronto Hospital, Weston, “adequately” treated and discharged by medical consent between January 1954 and June 1956. It is not an account of a study carefully planned in advance, but a retrospective report of results obtained by treatment then in vogue (namely long-term chemotherapy with at least two drugs, but usually three, for a period of one year, and surgical measures where these seemed to be indicated). The total number of all patients discharged during this time was 1,734. Of these, 850 were considered suitable for review in that they satisfied our criteria of adequate treatment. Six hundred and forty-eight were actually traced and of these 20 have relapsed to date (June 1958); 5 more were re-admitted because of recurrence of symptoms of pulmonary disease, but reactivation could not be established; 6 patients died of causes other than tuberculosis. The relapse rate is thus 3·1 per cent. The relapse cases were studied in detail. The ages ranged from 22 to 67 years and 10 of the 20 patients were aged 40 years or less at time of relapse. Eight were females and 12 were male patients. Sensitivity to drugs was complete in 11, unreported in 3, and in 2 patients tubercle bacilli were not cultured. Partial resistance only to one drug was encountered in the remaining 4 patients. Only one of the 20 patients had a resection (lobectomy) performed, but 3 had thoracoplasty as part of their treatment before relapse. It is of interest that in 4 patients resection was considered necessary but was not done for various reasons. This study seems to confirm tentative conclusions previously held by us regarding predisposition to relapse after treatment.

A.C. Ronald

J.F. Stitt

Effect of adequate long-term chemotherapy on relapse in pulmonary tuberculosis

长期充足化疗对肺结核复发的影响

Chest disease and morbidity has been studied among a group of 31 persons (grain workers, oil and flour millers, flour packer) exposed to inhaling mixed vegetable dusts at work. Pulmonary fibrotic lesions or simple pneumoconiosis were found histologically in 4 out of 5 cases in which post-mortem examination was done. Radiologically, various types of lung damage (reticulation, micro-nodulation, irregular fibrosis) were encountered, conforming with the histological findings in 4 out of the 5 cases in which we were able to obtain post-mortem examination. Emphysema associated with this and other types of occupational lung disease has been discussed, and 10 cases of tuberculosis and 2 of bronchogenic carcinoma have been noted. Only in six cases were chest appearances normal.

L. Dünner

R. Hardy

E. Nakielny

L.B. Robinson

G.A. Smart

Pneumoconiosis in grain workers, oil and flour millers

谷物工人、油磨工和面粉磨工的尘肺病

The value of scalene node biopsy as a diagnostic procedure in intrathoracic disease is established beyond doubt. The percentage of positive biopsies depends on the thoroughness with which the operation is carried out and is especially high in cases of sarcoidosis. The results of the present study bear out the author's previously published views on the lymphatic drainage of the lungs and give a guide to the question of which side should be explored. Right-sided lesions always give rise to pathological changes on the right. In cases where no lymph nodes are palpable, the right supraclavicular region should be explored irrespective of whether the lesion in the chest is on the left or right. Similarly, in bilateral lesions a right scalene node biopsy is advised. Only when the left supraclavicular nodes are palpable should this side be operated upon. A bilateral exploration is only justifiable where a right scalene node biopsy is negative and the case cannot be diagnosed by any other means.

H.C. Nohl

The value of scalene node biopsy in intrathoracic disease

斜角肌结节活检在胸内疾病中的价值

Publication Information	Publisher: Bailliere Tindall Ltd，Publishing cycle: ，Journal Type: journal，Open Access Journals: No
Basic data	Year of publication: 1943，Proportion of original research papers: ，Self Citation Rate:， Gold OA Rate:

British Journal of Tuberculosis and Diseases of the Chest

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