B and T cells constitute the majority of infiltrating lymphocytes in the kidney and represent the local perpetrators in lupus nephritis (LN), but the underlying pathogenic mechanisms are not well elucidated. The aim of this study is to explore the kidney-specific adaptive immune landscape in patients with active LN at the single-cell level.

Chunmei Wu

Shan Jiang

Zechuan Chen

Teng Li

Xixi Gu

Min Dai

Fang Du

Yan Ye

Longhai Tang

Mingyuan Wang

Xiaodong Wang

Ting Li

Shuang Ye

Chunde Bao

Xiaoming Zhang

Qiong Fu

Annals of the Rheumatic Diseases

风湿病年鉴 (ARD) 是一份国际同行评审期刊，致力于促进最高标准的科学交流和教育。它涵盖了风湿病学的所有方面，包括肌肉骨骼疾病、关节炎疾病和结缔组织疾病的谱系。 ARD 发表基础、临床和转化科学研究。鼓励简明的科学交流，并以同行评审的国际会议论文集为特色。教育论文包括最先进的评论、“如何”文章和教育案例，重点关注临床实践中面临的问题。该杂志于 1939 年首次出版，拥有权威的全球编辑委员会和不断增长的国际读者群。

The Annals of the Rheumatic Diseases (ARD) is an international peer-reviewed journal dedicated to promoting the highest standards of scientific communication and education. It covers all aspects of rheumatology, including musculoskeletal disorders, arthritic diseases, and connective tissue diseases. ARD publishes basic, clinical, and translational scientific research, encouraging concise scientific communication and featuring peer-reviewed conference proceedings. Educational papers include cutting-edge reviews, 'how-to' articles, and educational cases, focusing on issues faced in clinical practice. Since its first publication in 1939, the journal has maintained a prestigious global editorial board and a growing international readership.

《Annals of the Rheumatic Diseases》（风湿病年鉴，ARD）是一份国际同行评审的学术期刊，旨在促进高标准的科学交流与教育。期刊涵盖风湿病学的各个方面，包括肌肉骨骼疾病、关节炎和结缔组织疾病等。ARD发表基础研究、临床研究和转化科学研究，鼓励简洁明了的科学交流，并定期刊登国际会议的同行评审论文。教育类论文包括前沿评论、实用指南和教育案例，重点关注临床实践中遇到的问题。该杂志自1939年创刊以来，拥有权威的全球编辑委员会和不断扩大的国际读者群。

Single-cell transcriptomics reveal potent extrafollicular B cell response linked with granzyme K<sup>+</sup>CD8 T cell activation in lupus kidney

单细胞转录组学揭示与粒酶K<sup>+</sup>CD8 T细胞激活相关的狼疮肾中强大的滤泡外B细胞反应

Category	Quartile
医学	1
医学, 风湿病学	1

Single-cell transcriptomics reveal potent extrafollicular B cell response linked with granzyme K⁺CD8 T cell activation in lupus kidney

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Journal Info

Single-cell transcriptomics reveal potent extrafollicular B cell response linked with granzyme K+CD8 T cell activation in lupus kidney

ivySCI AI Smartly Parses PDF, Answers Researchers' Questions, and Helps You Understand Papers in Seconds

Journal Info

Single-cell transcriptomics reveal potent extrafollicular B cell response linked with granzyme K⁺CD8 T cell activation in lupus kidney